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ARE HYALURONIC ACID INJECTIONS EFFECTIVE FOR TREATING MARIONETTE LINES ?

Dernière mise à jour : 12 June 2026

Marionette lines are vertical lines between the corners of the lips and the chin. They are a frequent concern during aesthetic medicine consultations because they change facial expression, creating a stern, tired or sad appearance. Their development is multifactorial and mainly results from combined volume loss in the lower third of the face, gradual bone resorption in the jaw and chin, deep fat compartment loss and skin thinning. These changes cause loss of structural support and downward tissue descent, creating a visible crease between mouth and chin. Hyaluronic acid injections correct them effectively and are now the reference medical treatment for softening marionette lines and restoring lower-face balance.

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The formation of marionette lines 

The effectiveness of hyaluronic acid injections cannot be assessed properly without a precise understanding of the mechanisms responsible for marionette lines. These are not simple superficial wrinkles. They result from a structural imbalance in the lower third of the face. With age, mandibular bone resorption reduces chin projection and changes the mandibular angle. This loss of bone support causes gradual soft tissue descent. Meanwhile, loss of deep and superficial fat compartments accentuates volume loss. With less collagen and elastin, the skin becomes thinner and less resistant to mechanical stresses. These combined factors produce a pronounced vertical fold connecting the lip corner to the chin. Anatomical and clinical studies show that correcting these folds requires restoring structural support rather than simple superficial filling.

How hyaluronic acid works in treating marionette lines

Hyaluronic acid is a polysaccharide naturally present in the skin's extracellular matrix. In aesthetic medicine, it is used as injectable gels to restore volume and support facial structures. For marionette lines, its effectiveness relies on recreating volume support and improving hydration and tissue density. Injected deeply, it restores projection and structural support to the lower third of the face. This indirectly repositions tissues and reduces fold depth. A more superficial injection of very lightly cross-linked hyaluronic acid, such as a Skinbooster, into the fold itself can then smooth the skin crease forming a superficial fine line.
Injection of the wrinkle is often preceded by non-surgical lifting techniques intended to raise the sagging tissues responsible for the marionette line.

Effectiveness of hyaluronic acid injections for marionette lines

Available clinical data confirm the effectiveness of hyaluronic acid injections in correcting marionette lines when performed through an overall anatomical approach. Studies show significant improvement in fold depth and lower-face harmony after restoring supporting volume. Effectiveness is particularly notable when treatment extends beyond the fold itself to correction of the chin, jawline and surrounding volume. This strategy corrects the fold's structural cause rather than only its visible manifestation. Patients generally describe improved facial expression, perceived as more relaxed and less stern. The result is immediate after injection and stabilises within days.

Overall approach to the lower third of the face

Treating marionette lines in isolation often produces an incomplete or artificial result. Correction limited to directly filling the fold can weigh down the area and accentuate tissue descent. The modern approach relies on overall analysis of the lower third of the face. It includes assessing chin projection, jawline definition, skin quality and muscle dynamics. Restoring structural support through deep injections tightens tissues and reduces fold depth. Only after this step is direct fold treatment considered if needed. This strategy produces a more natural, lasting result consistent with the whole face.

Expected results and duration of effectiveness of hyaluronic acid injections into marionette lines

Hyaluronic acid injections provide visible, immediate improvement in marionette lines. The fold looks softer, the transition between lip corner and chin becomes more harmonious and overall facial expression improves. The aim is not to remove folds at the expense of naturalness, but to soften them naturally to preserve expression. Result duration varies with product type, injection depth and the patient's metabolism. On average, results last between twelve and eighteen months. Regular maintenance prolongs them and preserves lower-face balance.

Limitations and indications

Despite their effectiveness, hyaluronic acid injections have limitations. When marionette lines mainly reflect substantial skin laxity, correction solely through volume restoration may be insufficient. In these situations, combined management to improve skin quality and dermal density may be necessary. The indication must always follow a precise clinical examination. Analysing skin quality, bone structure and volume distribution determines whether injections are the most appropriate solution.

Dr Valeria Romano

Article written by Dr Valeria Romano

Dr Valeria Romano supports each patient through a comprehensive approach to facial, body and intimate aesthetics, as well as skin and hair quality. Every treatment is based on a personalised medical assessment.

Learn more about Dr Valeria Romano
Contact Dr Valeria Romano : +41 78 209 02 89 dr.romano.valeria@gmail.com

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