What is skin ageing ?
Skin ageing encompasses morphological, functional and biological changes that gradually affect skin. It has two components.
The first, intrinsic ageing, is linked to age, genetics and hormonal changes ; it involves slower cell division, declining collagen and elastin and loss of natural hyaluronic acid.
The second, extrinsic ageing, depends on environmental factors, particularly ultraviolet radiation, pollution and smoking.
These external aggressors generate oxidative stress, accelerating dermal fibre breakdown, impairing microcirculation and changing pigment distribution. In both cases, the epidermis thins, the barrier weakens and skin loses its ability to maintain deep hydration.
What are the signs of skin ageing ?

Visible ageing signs generally appear gradually.
The first changes concern quality and radiance : texture becomes less even, the complexion less luminous and suppleness declines.
Expression wrinkles, caused by repeated facial muscle contraction, develop on the forehead, glabella and around the eyes. Over time, they become established and permanent. Laxity is an important ageing sign : as collagen declines, tissues lose natural support, reducing jawline definition and causing gradual sagging.
Meanwhile, pigmentation spots can appear, particularly on sun-exposed areas such as the face, neck or hands. Skin may become drier, more fragile and thinner, accentuating an aged appearance.
What are the symptoms of premature skin ageing ?
Premature ageing means skin signs appear earlier than the natural ageing rate would suggest. Several signs warrant attention : visible wrinkles before 30, uneven tone despite a healthy lifestyle, or early pigmentation. Reduced jawline firmness and unusual dryness also indicate excessive exposure to external aggressors.
UV rays, particularly UVA, play a major role. They directly damage collagen fibres, oxidise cell membranes and accelerate laxity. Further aggravating factors include : smoking, urban pollution, certain medications and chronic lack of sleep. Together, they create oxidative stress causing premature ageing.

Which body area ages first ?
Some areas are more susceptible to ageing because of thin skin or constant external exposure. The eye contour, with particularly thin skin and few sebaceous glands, quickly develops fine lines and early laxity. The mouth contour is also delicate and subjected to repeated movements. The forehead, often sun-exposed, quickly develops pronounced expression lines. The neck and décolletage, often neglected in skincare, undergo substantial pigment and structural ageing. Finally, constantly exposed hands develop pigmentation spots and increasingly visible volume loss with age.
Causes of skin ageing
Skin ageing mechanisms are now clearly established.
The skin gradually loses fibroblast numbers and activity. These cells, essential for firmness and elasticity, naturally produce collagen, elastin and hyaluronic acid. Over time, synthesis slows, reducing density, hydration and mechanical resilience. Hormonal changes — particularly from menopause onwards — intensify this : sebaceous gland activity declines and the hydrolipidic film becomes more fragile.
The sun remains the leading cause of premature ageing. UV rays damage supporting fibres, slow collagen production and encourage brown spots. Pollution causes subtle but constant inflammation that accelerates ageing. Smoking reduces tissue oxygenation through blood vessel constriction ; skin then renews more slowly and loses radiance.
Finally, a diet low in antioxidants, chronic dehydration and insufficient sleep lastingly weaken skin structure and encourage ageing signs.
What accelerates skin ageing ?

Several factors accelerate skin ageing.
The first is unprotected sun exposure. UVA rays, present even in cloudy weather throughout the year, penetrate the deep dermis and gradually degrade collagen and elastin fibres, causing irreversible laxity.
Climate also plays an important role. Geneva's dry winter cold, combined with dry heated indoor air, encourages substantial hydration loss and weakens the barrier. Unsuitable care, such as abrasive cleansing and repeated alcohol-containing or irritating products, further damages the epidermis over time.
Lack of sleep and an overworked lifestyle disrupt cell renewal. Chronic stress stimulates cortisol production, reducing natural repair capacity. Finally, a diet low in essential fatty acids and antioxidants deprives cells of nutrients essential for protection and regeneration.
How can skin be rejuvenated ?
Managing skin ageing combines synergistic treatments selected according to skin type, age, patient goals and ageing signs. A comprehensive approach achieves harmonious results without changing facial expression.
Skinboosters are essential for deep hydration and dermal thickening. This lightly cross-linked hyaluronic acid improves density, suppleness and luminosity. It particularly suits thin, dry or sun-weakened skin, restoring more even consistency and lasting radiance.
Two techniques complement each other for established wrinkles. Hyaluronic acid fills static wrinkles or lifts certain areas through medical lifting, restoring volume and improving contours. Botulinum toxin mainly treats certain expression lines by reducing excessive muscle contraction.
Medium peels effectively improve surface quality. They promote renewal, even tone, reduce fine lines and correct pigmentation irregularities. Results are quick, but social downtime is required. One to two sessions suffice.
Fractional ablative laser is among the most effective treatments for skin ageing. Microscopic zones of controlled regeneration intensely stimulate collagen production and significantly increase dermal density. It reduces superficial wrinkles and corrects pigmentation. Four sessions spaced two months apart provide comprehensive, lasting rejuvenation.

Preventing skin ageing
Prevention is essential in managing skin ageing. It delays visible signs and preserves good quality over the long term. Its aim is to maintain cellular activity, strengthen tissues and retain sufficient hydration for supple, firm and radiant skin.
Mesotherapy delivers vitamins, minerals, amino acids and non-cross-linked hyaluronic acid. It improves tissue oxygenation, revives radiance and optimises tone. Combined with a PRX-T33 peel (known as mesopeel), which intensively stimulates synthesis of dermal components without social downtime, it is a particularly effective preventative approach. Two sessions yearly generally preserve more resilient, radiant skin.
Hydrafacial deeply cleanses, removes impurities and provides immediate hydration. It facilitates active ingredient penetration, improves quality and restores radiance. Twice-yearly treatment helps maintain healthy, hydrated skin.
Laser photorejuvenation stimulates collagen production and substantially increases dermal density. It can be performed once or twice yearly
Skinboosters also play a preventative role. They provide deep hydration, improve dermal suppleness and delay wrinkles. One to three syringes injected annually help preserve skin quality lastingly.
Results
Scientific evidence confirms results from these procedures. Several international publications demonstrate Skinboosters' effectiveness in improving hydration and elasticity, particularly in the Journal of Cosmetic and Laser Therapy. Extensive research also establishes hyaluronic acid's role in restoring volume and reducing wrinkles, as shown in the Aesthetic Surgery Journal. Botulinum toxin has decades of clinical experience and extensive literature confirming its lasting reduction of certain expression lines. Peels have proved valuable for reviving radiance, reducing fine lines and correcting pigmentation irregularities, regularly reported in the Journal of the American Academy of Dermatology. Finally, Lasers in Surgery and Medicine recognises fractional ablative laser as a standard treatment to increase dermal density and reduce superficial wrinkles. Together, these techniques provide gradual, natural rejuvenation supported by robust scientific evidence.
Skin rejuvenation treatment prices
Skin rejuvenation prices depend on technique, treated area and extent of ageing. Skinboosters, improving skin quality, cost 400 CHF per syringe. Hyaluronic acid injections, filling static wrinkles or supporting facial structures, cost 600 CHF per syringe. Botulinum toxin to reduce expression lines starts from 250 CHF for one area. Medium peels start from 500 CHF per session, depending on treatment extent. Fractional ablative laser sessions to increase density and correct superficial wrinkles cost 900 CHF. Mesotherapy and PRX-T33, used for prevention or radiance improvement, cost 500 CHF. Hydrafacial costs 200 CHF per session, while photorejuvenation sessions cost 500 CHF.
In a study involving fifty patients, three non-ablative fractional laser sessions reduced sun-related wrinkles and skin irregularities. Improvement, assessed in photographs, remained visible nine months after treatment. These results concern the laser and protocol studied.
In a randomised trial, poly-L-lactic acid injections were compared with no treatment for cheek wrinkles. At twelve months, improvement of at least one grade was observed in 71.6% of treated patients, compared with 26.1% of controls. Patients also reported satisfaction with skin firmness, radiance and the natural appearance of the result. These data concern the product and protocol assessed.
A series of 730 patients shows that fractional lasers can improve several signs of sun-related ageing. Fractional CO₂ laser gave better results for wrinkles, while another wavelength was more effective for pigmentation irregularities. These observations help select the laser according to the goal: smoothing the skin, evening out complexion or treating both problems.
Frequently asked questions about skin rejuvenation in Geneva
At what age is skin ageing treatment appropriate ?
Prevention can begin in the thirties, when collagen and elastin production declines and early fine lines appear. Early action slows ageing progression and maintains more resilient skin.
Are rejuvenation treatments painful ?
They generally cause little pain. Injections use fine needles or cannulas. Local anaesthesia is often applied for laser sessions.
How long do anti-ageing treatment results last ?
Botulinum toxin results last 4 to 6 months, and hyaluronic acid 9 to 12 months. Skinbooster effects remain visible for one year, and medium peels and lasers for several years.
Can work be resumed immediately after treatment ?
Yes, after most treatments such as botulinum toxin, hyaluronic acid, mesotherapy, Skinboosters or Hydrafacial. Medium peels and fractional ablative laser require social downtime ranging from a few days to one week.
Could injections change facial features ?
No, when performed precisely. Botulinum toxin softens contracted areas without freezing them, and hyaluronic acid restores volume naturally. Features and expression are preserved.
Can several treatments be combined in one protocol ?
Yes. Combining techniques addresses multiple ageing mechanisms for harmonious, lasting rejuvenation while preserving natural results.
Do anti-ageing treatment results appear quickly ?
Some are immediate, particularly hyaluronic acid injection results. Botulinum toxin works within days, while Skinboosters, mesotherapy, peels and lasers provide gradual results over several weeks.
Can skin ageing really be slowed ?
It cannot be stopped, but can be significantly slowed. Regular skincare, daily sun protection, a healthy lifestyle and medical follow-up maintain quality and preserve youthful appearance for longer.
