WRINKLE FILLING
BY INJECTION

Wrinkle treatment with injections is an aesthetic medicine procedure that helps correct wrinkles, restore facial volume, and improve skin quality without surgery. Depending on the type of wrinkle (dynamic, static, or age-related), different techniques may be used, including hyaluronic acid injections, botulinum toxin, Skinboosters, chemical peels, and laser treatments. Results are natural, immediately visible for some treatments, and typically last from several months to one year. A personalised approach is essential to achieve harmonious results tailored to each patient's ageing process.
In Geneva, Dr Romano specialises in facial aesthetic injections for wrinkle treatment using hyaluronic acid, botulinum toxin, and Sculptra®. She carefully selects products recognised for their quality and adapts each injection technique to the patient's individual facial anatomy in order to achieve natural and harmonious results.

Key information on wrinkle treatment

  • Anesthesia : none
  • Social downtime : none if injections, 7-10 days if laser or peel
  • Pain : 2/10
  • Duration of results : dynamic wrinkles : 6 months ; static wrinkles : 9 to 12 months if hyaluronic acid injections, years if medium peel
  • Hyaluronic acid : patient satisfaction : 85–95% , immediate result
  • Botulinum toxin : patient satisfaction : 80–90% , result after 10-15 days
  • Laser and peels : patient satisfaction : 85–95% , result after 3 months
  • Improvement of wrinkles : up to 60–80% correction depending on depth

Data from clinical studies on wrinkle filling

  • A review published in the Journal of Clinical and Aesthetic Dermatology shows that skin ageing primarily results from the progressive loss of collagen, elastin, and hyaluronic acid, combined with the effects of ultraviolet radiation and intrinsic ageing.
  • A review published in Plastic and Reconstructive Surgery demonstrates that combining botulinum toxin, hyaluronic acid, and collagen stimulators provides the best outcomes for overall facial rejuvenation while preserving a natural appearance.
  • The American Academy of Dermatology (AAD) recommends early wrinkle management combining daily photoprotection, appropriate skincare, and personalised medical treatments to effectively slow skin ageing.
  • The American Society for Dermatologic Surgery (ASDS) highlights that botulinum toxin injections, dermal fillers, laser treatments, and collagen-stimulating technologies are the main medical approaches used to correct wrinkles and help prevent their progression.

Contents

How can you rejuvenate without surgery ?

How to look 10 years younger without surgery ? What is the most effective treatment against wrinkles ? These questions are frequently asked during consultation.
Wrinkles are one of the first signs of aging. Some people find them charming, while others wish to eliminate them.
Medical techniques make it possible to :

  • Smooth out wrinkles.
  • Fill wrinkles.
  • Prevent wrinkle formation.
  • Improve wrinkles.

Marionette lines

Barcode lip lines

Frown lines

Forehead wrinkles

Crow's feet wrinkles

Nasolabial fold

Sleep lines

Smile lines

Fine lines

What are wrinkles ?

Wrinkles are depressions of varying depth that appear with age. They initially affect the surface of the skin (epidermis and superficial dermis) and gradually deepen to reach the middle and deep dermis. Depending on their depth, they are referred to as fine lines or wrinkles. If the wrinkle is very deep and associated with a loss of subcutaneous tissue, it is called a fold.

What are the different types of wrinkles ?

Wrinkles are folds, depressions or creases that appear on the skin due to natural aging, repeated expressions, exposure to the sun and other environmental factors. They can be classified into three main categories.

  • Expression lines or dynamic wrinkles : these wrinkles form due to repeated movements and therefore the activity of facial muscles. They are often found around the eyes (crow’s feet), the mouth (smile lines) and on the forehead (horizontal wrinkles).
  • Static wrinkles or resting wrinkles : these wrinkles are caused by a break in the skin and are visible at rest.
  • Aging wrinkles : with age, the production of collagen and elastin decreases, the skin loses its elasticity and firmness, leading to the appearance of deep and pronounced wrinkles.

How to prevent wrinkles ?

photo how to prevent facial wrinkles

To prevent the appearance of wrinkles and prolong the results of aesthetic treatments, it is essential to follow a suitable skincare routine.

  • Hydration : use moisturizing creams rich in active ingredients such as hyaluronic acid to maintain the skin’s hydration and suppleness.
  • Sun protection : apply a broad-spectrum sunscreen with an SPF of at least 30 daily to protect the skin from UV-induced damage.
  • Healthy diet : adopt a diet rich in antioxidants, vitamins, and essential fatty acids to nourish the skin.
  • Healthy lifestyle : avoid smoking, limit alcohol consumption and get enough sleep to allow the skin to regenerate.

What are the expected results of wrinkle filling ?

photo injection of wrinkles in Geneva

The results of wrinkle filling by injection are :

  • Visible reduction of wrinkles and fine lines : the result of expression line treatment lasts about six months, while that of static wrinkles lasts about one year.
  • Restoration of facial volume.
  • Enhancement of facial contours.
  • Improvement of skin density and hydration : hyaluronic acid enhances the hydration and quality of the skin. This gel attracts and retains water, increases skin elasticity and suppleness, and allows for overall rejuvenation.

What precautions should be taken before a wrinkle-filling session ?

photo instructions before face injection

Before a wrinkle-filling session, it is important to take certain precautions in order to benefit from an effective and safe treatment. 

  • Choose the right doctor : choose an experienced doctor. A preliminary consultation will allow your skin to be assessed, your expectations to be discussed, the most appropriate treatment to be determined, and any contraindications to the treatments to be ruled out. 
  • Medical history : inform your doctor about your medical history, including any allergies and medications you are taking.
  • Avoid certain medications and supplements : supplements and natural products such as vitamin E, ginkgo biloba, ginseng, and fish oil should be discontinued at least one week before the treatment, as they can increase the risk of bleeding. The discontinuation of anticoagulant and antiplatelet medications should only be done if authorized by the prescribing doctor and according to their specific instructions.
  • Prepare the skin : avoid aggressive skin treatments such as chemical peels, exfoliants, or laser treatments in the days leading up to the session, as the skin should not be irritated.

How do wrinkles appear ? What are the causes of wrinkles ?

photo causes wrinkles

Several factors are responsible for the appearance of wrinkles.

  • Age : over time, the production of collagen and elastin fibers decreases. The skin becomes thinner and more fragile. The speed of this process is genetically determined.
  • Hormones : the decline in trophic hormones for the skin accelerates its aging, which occurs during menopause and andropause.
  • Smoking and alcohol.
  • Lack of hydration.
  • The positions we adopt : pillow wrinkles (wrinkles appearing on one side of the face) and wrinkles between the breasts are caused by sleeping on the side.
  • Sun exposure : it is the main factor of extrinsic aging. The sun dehydrates the skin, causes pigmentation and alters the synthesis of collagen and elastin fibers.
  • Stress : stress is responsible for the formation of free radicals and alters skin circulation.
  • Lack of sleep.
  • Diet : a diet rich in fiber, fruits and vegetables, healthy fats (omega-3 and omega-6), with an adequate protein intake, slows down aging. A diet high in refined sugars and unhealthy fats accelerates it.
  • Lack of physical activity.

How to remove wrinkles from the face ?

There are several techniques to erase wrinkles.
Anti-aging treatments and anti-wrinkle creams are ineffective.
A clinical examination is performed to identify the type of wrinkle and propose the most suitable solution. Wrinkles have different causes, and their treatment is therefore personalized.

Hyaluronic acid injections to fill facial wrinkles

Hyaluronic acid injections are today one of the most popular treatments to correct facial wrinkles, restore lost volume and improve skin hydration. Hyaluronic acid is a substance naturally present in the body; when injected in a targeted way, it fills hollows and restores support to tissues weakened over time. This treatment provides immediate results, giving the face a naturally rejuvenated appearance without altering its expression.
Performed precisely by an experienced doctor, this treatment delivers long-lasting and very natural results.
Two techniques are used.

  • Wrinkle filling : the product is injected along the entire length of the wrinkle. The depth of injection and the type of product used depend on the specific wrinkle.
  • The lifting technique : often a fold accompanies a wrinkle; in this case, the sagging tissues must be lifted using the medical lifting technique with hyaluronic acid injections.

Botulinum toxin

Botulinum toxin reduces expression lines by temporarily decreasing the contraction of the muscles responsible for their formation. It is primarily indicated for the treatment of frown lines, forehead lines, and crow’s feet.

Skinbooster to reduce wrinkles

Skinboosters offer a discreet and progressive approach to improving skin quality and reducing fine lines. This very fluid, lightly cross-linked hyaluronic acid acts as a “deep hydration treatment,” intensely nourishing the dermis.
Unlike volumizing injections, Skinboosters do not alter the structure of the face : they strengthen the skin from within, improving its firmness, elasticity and natural radiance. This treatment is particularly suitable for dehydrated, thin, dull skin, or skin marked by sun exposure and aging. The results develop gradually over the sessions : the skin texture becomes smoother, fine lines fade and the complexion appears more luminous — a true Skin Radiance. It is an ideal treatment for preventing skin aging or complementing other aesthetic techniques.

Sculptra®

Sculptra® is an injectable treatment designed to gradually restore skin quality and firmness by stimulating the body's natural collagen production. It is indicated to correct age-related volume loss and progressively improve the facial structure. Results develop gradually over a period of 3 to 6 months.

Peels for wrinkles

Medical peeling is a rejuvenation technique that consists of exfoliating the skin in a controlled way through the application of a chemical solution. Depending on the type of peeling chosen — superficial, medium or deep — it can enhance skin radiance, reduce fine lines, densify the skin and stimulate collagen production. By promoting cell renewal, peeling helps eliminate visible imperfections, pigment spots and the first signs of aging. This treatment is often performed as a course (several sessions are required, except for medium and deep peels) to achieve smoother, more even, and visibly rejuvenated skin. Peeling is an excellent solution to restore a radiant complexion and treat wrinkles gently, for a long-lasting skin radiance effect.

Facial wrinkles erased by laser resurfacing

Resurfacing laser is a technology that treats deep wrinkles, scars, pigment spots and skin laxity. By delivering controlled energy to both the surface and deeper layers of the skin, this technique intensely stimulates collagen production and promotes complete tissue regeneration. After the treatment, the skin gradually renews itself : it becomes firmer, smoother and visibly rejuvenated. Wrinkles and fine lines fade, the skin’s quality improves and the complexion becomes more even. This treatment may require some recovery time, but it is ideal for patients seeking visible and long-lasting results. Performed by an experienced doctor, a resurfacing laser session achieves true skin renewal with a lifting effect without surgery.

Wrinkle treatment prices

In Geneva, the price of wrinkle treatment with hyaluronic acid is CHF 600 per syringe. Botulinum toxin injections are available from CHF 350. A personalised quotation is provided for all other treatments.
The cost of wrinkle treatment depends on the technique used, the area to be treated, the product used and the quantity of product required.

Frequently asked questions about wrinkle filling

Which wrinkles can be treated ?

 All wrinkles can be improved, but the treatment depends on their type.

  • Expression lines (forehead, eyes)
  • Static wrinkles (at rest)
  • Deep wrinkles / folds

Hyaluronic acid injections are the most effective treatment to fill wrinkles.

Yes, if they are well performed, the result is subtle and natural.

From the appearance of the first wrinkles, for prevention or correction.

No, only very superficial wrinkles can improve with skincare.

One session is sufficient, with maintenance every 6 to 12 months.

Expression lines cannot be filled. Their treatment relies on botulinum toxin injections.
Filler injections can be performed within the skin to densify it and make it more resistant to muscular movements, which slightly improves expression lines.

We recommend exfoliating creams containing glycolic acid and dermatologically tested moisturisers.

To achieve this, it is necessary to act on all the factors responsible for the appearance of wrinkles. It is also important to watch your weight : avoid gaining too much, experiencing significant weight fluctuations, or losing too many kilos too quickly. 

Once static wrinkles have set in, they can only be treated using medical techniques. To slow the appearance of wrinkles, we need to act on their causes.

We recommend mixing about ten drops of argan vegetable oil and Coenzyme Q10 with your moisturizing cream.
The best natural anti-aging care remains a healthy lifestyle : hydration, a balanced and healthy diet, restorative sleep, proper skin cleansing and makeup removal, exfoliation, massages, regular physical activity, and sun protection.

  • Foods containing fibre, antioxidants and vitamins: fruit and vegetables.
  • Healthy fats : fatty fish, olive oil, eggs, avocados, nuts and seeds.
  • Certain proteins : plant-based proteins, fish and white meat. Red and fatty meats accelerate aging.

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