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WHAT SHOULD BE AVOIDED BEFORE A HYALURONIC ACID INJECTION ?

Last updated : 28 May 2026

Hyaluronic acid injections are safe, effective and very well-tolerated aesthetic medical procedures under optimal conditions. Although physician expertise is essential, result quality also depends on patient preparation.
Simple actions, habits or treatments may influence skin tissue quality at injection, responsiveness, haematoma or inflammation risk and proper product integration.
Here is what is best avoided in the preceding days for safe treatment and natural, lasting results.

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Avoid blood-thinning medicines

In the preceding days, ideally a week before hyaluronic acid injection, certain precautions are essential to limit minor bleeding or haematomas.

  • Avoid medicines such as aspirin, Ibuprofen and anti-inflammatory drugs.
  • Avoid blood-thinning medicines such as anticoagulants.
  • Avoid certain supplements such as omega-3, high-dose vitamin E, ginkgo biloba or concentrated turmeric, which may weaken capillaries and increase bruising risk.

Any current treatment must be assessed with the prescribing physician before interruption. Informing the injector about medicines or supplements is essential to adapt the protocol and ensure a safe, precise procedure without complications. Careful preparation directly contributes to result quality and faster recovery.

Do not consume alcohol for 24 to 48 hours beforehand

Even small amounts of alcohol affect microcirculation by dilating vessels and weakening capillaries. This may promote redness, minor bleeding or bruising. To limit effects and optimise quality, avoid all alcohol for 24 to 48 hours beforehand. Stable blood supply promotes better integration and faster recovery. This simple precaution supports safe, harmonious treatment without adverse effects.

Avoid certain aggressive or irritating cosmetics

In the days before hyaluronic acid injection, it is recommended to :

  • Avoid overly active or irritating skincare.
  • Avoid mechanical or enzymatic scrubs.
  • Avoid retinol, fruit acids (AHA, BHA) or highly concentrated serums that may weaken skin.

Sensitised skin reacts more strongly during injection : warmth, local inflammation or slower healing of needle entry points may occur.
A gentle, hydrating routine is preferable for preparation. Soothing, non-comedogenic products without aggressive fragrance strengthen the barrier, stabilise skin and improve tolerance. Healthy, balanced skin directly supports result quality and longevity.

Avoid aesthetic treatments the day before (or same day)

Aesthetic treatments the day before or on injection day are discouraged. Peels, microdermabrasion, laser or salon extractions temporarily stimulate skin and may cause mild inflammation, redness or barrier impairment. Increased sensitivity makes skin more reactive and may disrupt integration.
For optimal tolerance and even results, separate these treatments from injections by at least one to two weeks. This allows skin to regain balance and receive treatment under the best conditions.

Arrive without make-up

Arriving without make-up is recommended, particularly on treatment areas such as lips, folds or cheeks. Even light make-up may contain irritating or occlusive agents that weaken skin. It may introduce impurities or bacteria into needle-created microperforations, increasing irritation or inflammation risk.
Clean skin also facilitates disinfection and optimal hygiene. Gentle removal can be performed in the practice if needed, but arriving without cosmetic products is ideal. This simple precaution supports treatment safety and final quality.

Avoid injection with an active infection

Injection is strongly discouraged with any infection, even mild. Herpes, tonsillitis, sinusitis, cystitis or other active inflammation may interfere with integration. Irritation or lesions in the treatment area also require postponement. These situations weaken immune response and increase local inflammation, migration or unwanted small nodule risks.
For safety, injections will be postponed if general or skin health is uncertain. This vigilance ensures tolerance, quality and durability.

Avoid injection following recent vaccination

Spacing hyaluronic acid injections at least two weeks before or after vaccination is recommended. This avoids potential interaction between vaccine-related immune response and tissue integration. Although rare, unpredictable inflammatory responses may temporarily impair aesthetic results.
Inform your physician if vaccination is planned to adapt the treatment schedule. This simple coordination ensures procedural safety and long-term stability.

Conclusion : instructions before hyaluronic acid injection

Good preparation is essential for a safe, comfortable procedure and harmonious result. In the preceding days, avoid blood-thinning medicines or supplements such as aspirin, anti-inflammatory drugs or omega-3, and alcohol. Protect skin from irritation : no scrubbing, exfoliants, retinoids or recent peels. Postpone with infection, recent vaccination or skin irritation. On treatment day, skin should be clean, intact and make-up-free in treatment areas.
Clear discussion of medical history, current treatments and aesthetic expectations adapts the protocol to each patient. Careful preparation optimises tolerance, promotes integration and ensures a safe, natural and lasting aesthetic experience.

Dr Valeria Romano

Article written by Dr Valeria Romano

Dr Valeria Romano supports each patient with a comprehensive approach to the aesthetics of the face, body and intimate areas, and to skin and hair quality. Every treatment is based on a personalised medical assessment.

Learn more about Dr Valeria Romano
Contact Dr Valeria Romano : +41 78 209 02 89 dr.romano.valeria@gmail.com

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