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HYALURONIC ACID INJECTIONS IN GYNAECOLOGY : REVIEWS

Last updated : 28 May 2026

Hyaluronic acid injections in gynaecology now receive generally positive feedback from doctors and patients when performed for precise indications, particularly restoring labia majora volume and vaginal dryness. Scientific studies published in recent years report high satisfaction rates and a good safety profile. However, some indications have a stronger level of evidence than others.

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Are hyaluronic acid injections in gynaecology effective according to scientific studies ?

Effectiveness is the first criterion for assessing a medical treatment. In this respect, scientific data published over the past ten years are generally reassuring.
A review published in the Journal of Cosmetic Dermatology highlights that hyaluronic acid injections effectively restore the volume of the labia majora with a high rate of aesthetic satisfaction and a low complication rate. The authors conclude that this approach is an effective alternative to certain more invasive surgical procedures in patients with labia majora hypotrophy.
Similar results have been reported in Dermatologic Therapy, where the authors observe a significant improvement in the appearance of this area and a positive perception of results among patients after several months of follow-up.

Doctors' opinions on hyaluronic acid injections in the labia majora 

Doctors now regard hyaluronic acid as the reference treatment for correcting labia majora volume loss without surgery.
This position is explained by several characteristics of the product. Hyaluronic acid is biocompatible, absorbable and reversible. Its behaviour in tissues is thoroughly understood thanks to several decades of use in aesthetic medicine and reconstructive surgery.

What do patients say after an intimate hyaluronic acid injection ?

Satisfaction studies show that patients are among the main advocates of this technique.
In scientific publications on labia majora augmentation, satisfaction rates frequently exceed 80 to 90 % depending on the criteria studied.
Reported benefits mainly concern improved intimate aesthetics, restoration of age-related volume loss and greater self-confidence.
Several studies also indicate improved everyday comfort in women with significant fat loss in the labia majora. This improvement is particularly observed in menopausal patients or after significant weight loss.
It is interesting to note that patients often describe a psychological benefit greater than the purely aesthetic benefit. Correcting longstanding insecurities or improving body image seems to play an important role in overall satisfaction.

Scientific literature on the safety of gynaecological hyaluronic acid injections 

In a review published in Aesthetic Surgery Journal, the authors conclude that vulvar hyaluronic acid injections have a favourable safety profile when injection protocols are followed. The complications observed are minor and transient.
The most frequently reported side effects are moderate oedema, temporary tenderness or small bruises that disappear spontaneously within a few days.
The International Urogynecology Journal reports similar conclusions, highlighting the low rate of serious complications in published series.
However, the authors recall that treatment safety depends directly on the doctor's experience. Injections require an in-depth knowledge of vascular and nerve anatomy to avoid complications associated with poor technique.

Do hyaluronic acid injections improve intimate comfort according to studies ?

In the journal Menopause, several authors have studied the value of treatments intended to correct vulvar changes associated with hormonal ageing. The results suggest that restoring labia majora volume can improve the natural mechanical protection of vulvar tissues and help reduce certain feelings of discomfort.
In particular, some patients report reduced friction-related irritation, better tolerance of fitted clothing and improved comfort during certain physical activities.
However, researchers remain cautious. They recall that intimate comfort depends on many anatomical, hormonal and psychological factors. Hyaluronic acid is therefore only one element among others in the comprehensive management of women's intimate health.

Hyaluronic acid injections in gynaecology : is the overall opinion favourable ?

When doctors' opinions, patients' feedback and the conclusions of scientific publications are analysed together, a clear trend emerges : hyaluronic acid injections in gynaecology appear to be an effective, safe solution for restoring labia majora volume and improving certain aspects of intimate comfort. Studies published in the Journal of Cosmetic Dermatology, Dermatologic Therapy, Aesthetic Surgery Journal, International Urogynecology Journal and Menopause report generally positive results with high satisfaction and a low complication rate. Nevertheless, the authors emphasise the importance of rigorous patient selection and performance by a doctor specifically trained in intimate anatomy.

Dr Valeria Romano

Article written by Dr Valeria Romano

Dr Valeria Romano supports each patient with a comprehensive approach to the aesthetics of the face, body and intimate areas, and to skin and hair quality. Every treatment is based on a personalised medical assessment.

Learn more about Dr Valeria Romano
Contact Dr Valeria Romano : +41 78 209 02 89 dr.romano.valeria@gmail.com

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