Illustration of facial aesthetic treatments

FAILED NASOLABIAL FOLD INJECTION

Dernière mise à jour : 3 July 2026

Hyaluronic acid injection into nasolabial folds is a common procedure intended to soften signs of ageing and restore a gentler, more rested facial expression. However, despite its minimally invasive nature, some injections can be unsatisfactory or even cause temporary or longer-lasting undesirable effects. An "unsuccessful" nasolabial fold injection results from poor product selection, an incorrect indication or an unsuitable technique.
Understanding the causes and signs of inappropriate filling is essential for both doctor and patient to identify the most suitable solution : correction, monitoring or sometimes dissolving the product.

Book an appointment

Why can a hyaluronic acid nasolabial fold injection be unsuccessful ?

Nasolabial folds are both mobile and anatomically complex areas. They result from midface tissue sagging and loss of bone and fat support. Treating them involves restoring volume harmony rather than simply "filling a wrinkle".
Failing to consider this anatomical reality can lead to an unsatisfactory result even when the technical procedure appears well performed. It is therefore crucial to distinguish selection errors, technical errors and transient side effects.

What are the signs of an unsuccessful nasolabial fold injection ?

A poorly performed or unsuitable injection can produce several types of undesirable results, ranging from simple aesthetic discomfort to more serious complications. The main signs of an "unsuccessful" injection are :

An unattractive or unnatural result :

  • Overcorrection : the fold looks excessively filled, forming a visible ridge, especially at rest.
  • Asymmetry : one side of the face looks fuller or hollower than the other, disrupting the balance of the smile or face.
  • A frozen-looking face : the product is too dense or injected too superficially, causing visible stiffness during facial movements.
  • Product migration : hyaluronic acid moves slightly outside the fold, creating a palpable or visible irregularity.


Abnormal sensations or discomfort  :

  • Localised hardening : small lumps beneath the skin, often caused by poor tissue integration or a collection of product.
  • Painful tension : the patient experiences constant discomfort, sometimes worsened by facial expressions.
  • Persistent swelling : prolonged swelling beyond 7 to 10 days, which may indicate water retention or local inflammation.


Rare but more serious complications :

  • Bluish discolouration (Tyndall effect) : seen when product has been injected too superficially, particularly in thin skin.
  • Infection or inflammatory granuloma : persistent redness, pain, local warmth or inflammatory nodules require specific management.
  • Vascular complication : extremely rare but serious, this can occur if hyaluronic acid compresses or blocks a blood vessel. It presents with sudden pain, skin blanching and, without treatment, skin necrosis.

What causes an unsuccessful nasolabial fold injection ?

Although hyaluronic acid is widely used for its rapid, natural results, some injections may not produce the expected effect. Several factors associated with the product, technique or patient can explain these failures.

  • Unsuitable hyaluronic acid selection : using a gel that is too dense or insufficiently cohesive in a mobile area such as the nasolabial fold can produce a rigid result, noticeable visually or to the touch. Conversely, an overly fluid product in a deep fold will not produce a satisfactory result. Some products are specifically designed for this area. However, using these volumising hyaluronic acids in a superficial fold or thin skin risks excessive or unattractive correction.
  • Inappropriate injection technique : mastery of the injection plane (subcutaneous, preperiosteal, intradermal) is essential. Overly superficial injection increases the risk of the Tyndall effect, while overly deep injection may produce no result. The cannula is often preferred for its safety and even delivery, but requires good manual skill.
  • Incorrect indication or incomplete analysis : sometimes the nasolabial fold is treated in isolation, although it has developed because of volume loss in the cheekbones or temples. Injecting the fold without restoring the upper third of the face through filling or non-surgical lifting techniques is an inappropriate approach that fails to address the source of the problem.

How can an unsuccessful nasolabial fold injection be corrected ?

Fortunately, when a hyaluronic acid injection does not produce the expected result, different options exist to correct or improve the situation. Everything depends on the nature of the problem.

  • Waiting and monitoring : in some cases, undesirable effects are temporary. Swelling, slight asymmetry or hardening resolve spontaneously within two to three weeks. Rigorous medical follow-up is then essential.
  • Massage or localised correction : gentle massage can promote product integration. In some cases, a small targeted touch-up or dissolution of excess product can balance the result.

How can an unsuccessful nasolabial fold injection be avoided ?

The doctor's experience plays a central role in result quality. Complete facial anatomical knowledge, combined with personalised analytical ability, allows every injection to be adapted to the patient's facial structure and expectations. This expertise ensures a natural, harmonious and lasting result without overcorrection or rigid expressions.
Treatment success also depends on collaboration between patient and doctor. It is essential that the patient :

  • Clearly expresses aesthetic expectations to define a realistic, appropriate objective.

  • Reports any medical history or current treatment to ensure injection safety.

  • Understands that filling aims to restore balanced, natural facial dynamics rather than erase folds completely or freeze the features.

Finally, using high-quality hyaluronic acids selected according to skin type, fold depth and tissue mobility is an essential criterion for success. Combined with a mastered technique, this requirement guarantees a reliable, subtle and lasting result. In Geneva, consulting an experienced doctor therefore ensures patients receive safe care and results that meet their expectations.

Can another injection be performed after an unsuccessful nasolabial fold treatment ?

An unsuccessful nasolabial fold injection does not rule out successful correction later. Reinjection can be considered, but only under certain conditions. The initial product must have had time to be partially or fully absorbed. Any local reaction, whether inflammation or swelling, must also have resolved completely. Finally, the causes of failure must be analysed precisely, whether inappropriate product choice, technical error or an incorrectly chosen injection plane. When treatment can resume, it must be entrusted to an experienced doctor.

What should be done about an unsatisfactory result after a nasolabial fold injection ?

Although most unsuccessful injections involve poor execution or technical choices, some situations are associated with post-procedure behaviour that compromises the result : excessive massage of the injected area, heat exposure (sauna, steam room, intense exercise) within 48h, anticoagulant or anti-inflammatory medication not reported to the injecting doctor before injection, lack of follow-up or failure to follow medical instructions.
The patient's active commitment to following the post-injection protocol is essential for treatment success and durability.

Nasolabial fold injection performed by a non-doctor : what are the risks and options for recourse ?

Unfortunately, some unsuccessful nasolabial fold injections follow procedures performed by unauthorised people : beauticians, self-injections or unqualified practitioners working in countries with more permissive legislation. These situations expose patients to several dangers, such as non-compliant products, inadequate hygiene or increased risks of infection, necrosis or even irreversible damage. In Switzerland, only doctors trained in aesthetic medicine are authorised to perform hyaluronic acid injections. In the event of harm, medical and legal recourse may be sought through the competent health authorities.

Dr Valeria Romano

Article written by Dr Valeria Romano

Dr Valeria Romano supports each patient through a comprehensive approach to facial, body and intimate aesthetics, as well as skin and hair quality. Every treatment is based on a personalised medical assessment.

Learn more about Dr Valeria Romano
Contact Dr Valeria Romano : +41 78 209 02 89 dr.romano.valeria@gmail.com

Share this article