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HAS BOTULINUM TOXIN BEEN AROUND FOR A LONG TIME ?

Last updated : 4 June 2026

Botulinum toxin, better known to the public as botulinum toxin, has become one of the reference treatments in aesthetic medicine for reducing expression lines (forehead lines, frown lines, crow's feet), opening the eyes (eyebrow lift) or treating primary excessive underarm sweating. However, this substance, now synonymous with discreet rejuvenation, has a much longer history than one might imagine.
Before becoming a reference aesthetic treatment, botulinum toxin was first identified in a medical and scientific context, then tested in numerous disciplines before being adopted in aesthetic medicine practices.
Looking back at its development helps explain why botulinum toxin is a safe, well-mastered treatment validated by decades of clinical research.

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History of botulinum toxin

The history of botulinum toxin begins in the nineteenth century. It was first isolated following food poisoning, particularly cases involving consumption of poorly preserved cured meats. The word botulinum comes from the Latin botulus, meaning sausage.
It was not until the twentieth century that type A botulinum toxin was studied, purified and mastered in laboratories, particularly by American researchers. At that time, it began to be used at very low doses to treat muscular conditions such as strabismus, blepharospasm (involuntary eyelid blinking) and muscle spasticity.
These initial medical indications demonstrated that botulinum toxin, injected locally in small doses, could temporarily block muscle contraction without toxic effects.

Since when has botulinum toxin been used in aesthetic medicine ?

The introduction of botulinum toxin into aesthetic medicine dates back to the early 1990s in the United States. The first doctors to use it aesthetically did so during eye-area treatments, observing that patients treated for muscle spasms around the eyes also had fewer expression lines.
These results generated considerable interest. Injections gradually expanded to the forehead, then frown lines and finally other areas.
In Switzerland, particularly Geneva, botulinum toxin is now widely used by doctors. It has official authorisation and is among the most widespread treatments.

Is botulinum toxin a recent or well-established aesthetic treatment ?

Aesthetic botulinum toxin is considered to have been used for more than thirty years. In aesthetic medicine, this is a significant period. This experience establishes botulinum toxin as one of the best-documented treatments, with thousands of clinical studies published worldwide.
Botulinum toxin is used in more than eighty countries. It is approved by the strictest health authorities, particularly the FDA in the United States and Swissmedic in Switzerland. These bodies control not only product quality, but also indications, storage, traceability and long-term safety.
This level of validation makes it a reference aesthetic medicine treatment in Geneva for both women and men from the first appearance of dynamic wrinkles.

What are the recent developments in botulinum toxin treatments ?

Since its beginnings, botulinum toxin use in aesthetic medicine has evolved considerably. Injection techniques have become more precise and better adapted to each morphology.
Today, botulinum toxin is no longer limited to treating established wrinkles. It also forms part of a preventive approach from the thirties, particularly through Baby botulinum toxin, involving very low doses to gently relax upper-face muscles when dynamic wrinkles have a psychological impact, while preserving natural expressions.
Its scope has also expanded to functional indications with an aesthetic purpose, such as treating primary axillary hyperhidrosis (excessive sweating). 
These advances reflect a shift towards more considered, precise and personalised aesthetic medicine, where botulinum toxin becomes a genuine balancing tool serving facial harmony and overall well-being.

Why is botulinum toxin now considered a safe aesthetic treatment in Geneva ?

With more than thirty years of aesthetic medicine use, botulinum toxin is now recognised for reliability, safety and effectiveness. In Geneva, its use is strictly regulated : injections are performed by trained, experienced doctors. Products come exclusively from certified laboratories and benefit from full traceability, from manufacture to injection.
Before any procedure, the doctor performs an in-depth assessment : analysing muscle strength, possible asymmetries, the patient's aesthetic needs and medical history. This personalised approach ensures treatment that is safe, precise and adapted to each morphology.
When properly dosed and expertly injected, botulinum toxin does not freeze the face. It reduces wrinkles while respecting natural facial dynamics. Its fully reversible effect is an additional advantage for patients discovering treatment with confidence.

Conclusion : how long botulinum toxin has existed

Botulinum toxin is not a new or experimental product. It has been used medically for more than a century and in aesthetic medicine for more than thirty years. This experience, clinical practice and numerous regulatory controls now make it a reliable, safe and effective treatment, particularly when performed by an experienced doctor in Geneva.
Techniques evolve, doses are better controlled and results more natural. Botulinum toxin is now among the most effective tools for preventing skin ageing. It can be used occasionally or integrated into a comprehensive treatment strategy, then combined with other treatments such as hyaluronic acid, Skinboosters or mesotherapy.
To determine whether this treatment suits your face, a personalised medical consultation is the best option.

Dr Valeria Romano

Article written by Dr Valeria Romano

Dr Valeria Romano supports each patient with a comprehensive approach to the aesthetics of the face, body and intimate areas, and to skin and hair quality. Every treatment is based on a personalised medical assessment.

Learn more about Dr Valeria Romano
Contact Dr Valeria Romano : +41 78 209 02 89 dr.romano.valeria@gmail.com

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