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THE FACTS ABOUT MESOTHERAPY : EVERYTHING YOU NEED TO KNOW ABOUT MESOTHERAPY

Dernière mise à jour : 10 June 2026

Mesotherapy has a distinctive place in aesthetic medicine. A subtle, gradual technique that respects skin physiology, it appeals to many patients seeking better skin quality without visible transformation or changes in volume. Yet despite its growing popularity, mesotherapy is sometimes misunderstood, wrongly reduced to a simple hydration technique or confused with other types of injections.
Far from being a superficial or incidental treatment, it forms part of a comprehensive view of skin health, focused on prevention, maintenance and respect for natural ageing.

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Aesthetic mesotherapy

Mesotherapy has a distinctive place in aesthetic medicine. A subtle, gradual technique that respects skin physiology, it appeals to many patients seeking better skin quality without visible transformation or changes in volume. Yet despite its growing popularity, mesotherapy is sometimes misunderstood, wrongly reduced to a simple hydration technique or confused with other types of injections.
Far from being a superficial or incidental treatment, it forms part of a comprehensive view of skin health, focused on prevention, maintenance and respect for natural ageing.

What is mesotherapy in aesthetic medicine?

Mesotherapy is a medical technique involving the injection of very small quantities of active substances directly into the superficial dermis. Unlike volumising or structural injections, its purpose is not to alter features but to improve the skin's biological functioning.
The injections are made at a shallow depth and distributed throughout the treatment area. This approach acts locally, as close as possible to skin cells, optimising the bioavailability of active ingredients.
Mesotherapy is based on a simple principle: giving the skin what it needs, where it needs it, without overload or excess.

The substances used in mesotherapy

The products injected during mesotherapy are selected according to the desired goals and the patient's profile. They come as personalised cocktails combining different groups of substances.
The most common ingredients are vitamins, particularly B vitamins and vitamin C, minerals and trace elements, amino acids, antioxidants and non-cross-linked hyaluronic acid. The hyaluronic acid used in mesotherapy differs from that intended for filling. It is fluid, non-volumising and aims exclusively to improve skin hydration and quality. Combining these elements improves the skin's natural regeneration mechanisms.

The effects of mesotherapy on the skin

Mesotherapy acts gradually and comprehensively on the skin. It does not transform it but improves its internal functioning, producing visible, lasting benefits.
Its main effects are: improved skin hydration, greater suppleness, a brighter and more even complexion, and skin that is more resistant to external stressors.
By stimulating skin metabolism and microcirculation, mesotherapy makes the dermal environment healthier and more conducive to maintaining good-quality skin.

Mesotherapy and skin ageing

Skin ageing results from several combined processes: the skin retains moisture less effectively, its supporting fibres weaken and cellular activity slows. Mesotherapy does not aim to erase signs of ageing but to act earlier to slow certain mechanisms.
By improving hydration and skin function, this technique helps delay dryness-related fine lines, preserve suppleness, prevent a dull complexion and better protect the skin from external stressors, particularly climatic factors.
This preventive action explains why mesotherapy can be offered at different ages, with goals adapted to each stage of life.

Who is mesotherapy for

Mesotherapy is suitable for a wide range of people when the goal is improved skin quality rather than structural correction. It suits both women and men and can be performed on different skin phototypes and at different ages.
It may be indicated for:
• Young patients wishing to prevent skin ageing.
• Patients with dehydrated or dull skin.
• People exposed to stress, pollution or tobacco.
• Patients whose skin has been weakened by sun or cold.

Areas that can benefit from mesotherapy

Mesotherapy is not only indicated for the face. It can be used on several body areas, depending on the skin's needs.
The most frequently treated areas are the face, neck, décolletage, backs of the hands and scalp.

What happens during a mesotherapy session

A mesotherapy session always begins with a medical consultation. This allows the skin to be assessed, the patient's expectations to be understood and a suitable strategy to be defined.
Treatment then involves a series of superficial injections using a very fine needle. Dr Romano uses a mesotherapy gun. The sensations are generally well tolerated, with no discomfort felt. Recovery is straightforward, sometimes involving slight redness or small temporary bumps that disappear quickly.
Daily activities can be resumed immediately, making mesotherapy compatible with an active professional life.

Frequency and scheduling of sessions

Mesotherapy relies on regularity. Results develop gradually and depend on following an appropriate protocol.
Generally, initial treatment comprises several closely spaced sessions, followed by maintenance sessions at longer intervals. The doctor determines the exact schedule according to skin condition and the individual response to treatment. Mesotherapy is not a one-off miracle procedure but ongoing support.

The difference between mesotherapy and Skinboosters

Mesotherapy is sometimes confused with Skinboosters because both techniques aim to improve skin quality. However, their goals and methods differ.
Mesotherapy works mainly by supplying nutrients and stimulating skin metabolism.
Skinboosters rely essentially on injections of lightly cross-linked hyaluronic acid, with a longer-lasting hydrating effect.
These approaches are complementary rather than opposed. The choice depends on the skin's specific needs and the overall strategy defined during consultation.

The limitations of mesotherapy

Mesotherapy must be approached realistically and with medical understanding. This technique does not aim to correct pronounced skin laxity or erase wrinkles. Mesotherapy cannot alter facial volumes or replace structural treatments. Its value lies in being used for what it is: a treatment to improve skin quality and a technique for preventing skin ageing.

The safety and tolerability of mesotherapy

When performed by a trained doctor, mesotherapy has an excellent safety profile. The products used are biocompatible and the injected quantities are small.
Side effects are rare and usually mild: temporary redness, small bruises or a slight feeling of tightness. An appropriate indication and rigorous technique help limit side effects.

Dr Valeria Romano

Article written by Dr Valeria Romano

Dr Valeria Romano supports each patient through a comprehensive approach to facial, body and intimate aesthetics, as well as skin and hair quality. Every treatment is based on a personalised medical assessment.

Learn more about Dr Valeria Romano
Contact Dr Valeria Romano : +41 78 209 02 89 dr.romano.valeria@gmail.com

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