Portrait illustrant la qualité de la peau et le vieillissement cutané

How to prolong the results of botulinum toxin ?

Dernière mise à jour : 2 June 2026

Botulinum toxin is one of the most popular aesthetic treatments for certain dynamic wrinkles. In 2024, many people continue choosing this non-surgical solution to rejuvenate their face.
However, impressive though results are, they are not permanent and generally last 3 to 6 months. Tips and products can prolong its effects. This article explores best practices, aftercare and recommendations for keeping a fresh, youthful face longer.

Book an appointment

Botulinum toxin is one of the most popular aesthetic treatments for certain dynamic wrinkles. In 2024, many people continue choosing this non-surgical solution to rejuvenate their face.
However, impressive though results are, they are not permanent and generally last 3 to 6 months. Tips and products can prolong its effects. This article explores best practices, aftercare and recommendations for keeping a fresh, youthful face longer.

What is botulinum toxin and how does it work?

Botulinum toxin is a purified toxin blocking nerve signals to targeted muscles, preventing contractions causing expression lines. Relaxing these muscles smooths skin. It is indicated for forehead lines, frown lines (between eyebrows), crow's feet (around eyes) and primary axillary hyperhidrosis.
Treatment is quick and non-invasive, with results generally appearing 3 to 7 days after injection. Effects gradually fade as the body breaks down the toxin, making prolongation tips valuable for maintaining a youthful face as long as possible.

How long do botulinum toxin effects last?

Effects generally last 3 to 6 months depending on metabolism, contraction intensity and lifestyle. Muscles gradually resume activity and wrinkles return. Several tips and best practices can prolong effects.

How can you prolong botulinum toxin effects?

Following certain tips can prolong effects to 6-7 months.

Follow post-treatment recommendations

To maximise duration, carefully follow Dr Romano's post-treatment recommendations.

  • Avoid touching or massaging the treated area for at least 24 hours to prevent product movement.
  • Avoid all physical exercise for the first 48 hours to limit increased circulation that might accelerate breakdown or cause migration.
  • Avoid direct sun or extreme heat such as saunas for 48 hours to prevent skin inflammation or irritation.
  • Avoid shampooing the same day and eyebrow hair removal for two days.

Use peptide creams and serums

Peptides are amino acid chains stimulating collagen production and skin firmness. Some serums and creams contain specific peptides that can mimic botulinum toxin effects by relaxing facial muscles and reducing fine lines. Often called botulinum toxin-like products, they complement treatment to prolong results.
Many peptide or neuropeptide products are available. Several consumers report satisfaction, but no medical study has proved effectiveness.

Maintain optimal hydration

Well-hydrated skin tends to look smoother and firmer, helping prolong results. Moisturisers rich in hyaluronic acid are excellent for keeping skin hydrated and plump. Hyaluronic acid also increases elasticity.
Drinking plenty of water is additionally recommended to maintain hydration and prevent dryness encouraging wrinkles.

Adopt an anti-ageing skincare routine

To maximise botulinum toxin effects, adopt a suitable anti-ageing routine including regular use of products with anti-ageing ingredients.
Antioxidants (vitamins C, E, retinol) protect skin from free radical damage and improve quality.
Retinol promotes cell renewal and stimulates collagen production.
Sun protection is essential against premature UV-related ageing, which can shorten toxin effects by accelerating skin tissue degradation.

Schedule maintenance sessions

Regular maintenance every 5 to 6 months is recommended. However, do not wait for effects to disappear completely before another injection. A consistent schedule can prolong results, as facial muscles become accustomed to relaxation, weaken and contract less.

Combine botulinum toxin with other aesthetic treatments

A trend is combining botulinum toxin with other treatments to maximise and prolong results. Common complementary techniques are Skinboosters, radiofrequency, photorejuvenation laser and peels.

Maintain a healthy lifestyle

Lifestyle directly affects result longevity. Healthy habits can prolong treatment effects.
Avoid smoking: it is a major cause of premature skin ageing and can shorten toxin effects.
Manage stress: chronic stress promotes facial muscle contraction, potentially reducing effects.
Eat a balanced diet: consume antioxidant- and omega-3-rich foods to protect skin and maintain elasticity.

Products that help prolong botulinum toxin effects

To maximise duration, specific products help maintain smooth skin and prevent wrinkles returning.

“Botulinum toxin-like” serums and creams

Many such serums and creams promise prolonged effects by slightly inhibiting muscle contraction or deeply hydrating skin. Often peptide-based, they can complement your daily routine to enhance botulinum toxin action.

.

Dietary supplements for the skin

Some studies suggest collagen, hyaluronic acid or antioxidant vitamin C and E supplements help maintain firm, elastic skin, enhancing results.

Dr Valeria Romano

Article written by Dr Valeria Romano

Dr Valeria Romano supports each patient through a comprehensive approach to facial, body and intimate aesthetics, as well as skin and hair quality. Every treatment is based on a personalised medical assessment.

Learn more about Dr Valeria Romano
Contact Dr Valeria Romano : +41 78 209 02 89 dr.romano.valeria@gmail.com

Share this article