
What does mesotherapy contain?
Dr Romano personally prepares the mixtures of mesotherapy ingredients for injection, adapting them to the patient's needs. Treatment is tailored to ensure the best possible result.
A mixture of non-cross-linked hyaluronic acid, trace elements, minerals and vitamins is used.
- Hyaluronic acid: for its hydrating and regenerative properties.
- Vitamins: to stimulate cellular functions.
- Minerals: for ionic balance.
- Amino acids: for protein synthesis.
- Coenzymes: for skin metabolism.
- Nucleic acids: for cellular exchange.
- Antioxidants: to neutralise free radicals.
- Ingredients targeting hair growth for scalp mesotherapy (hair mesotherapy).
When should you have mesotherapy in Geneva?
Mesotherapy can be performed at any time of year.
Patients wishing to prevent signs of ageing or maintain radiant, healthy skin are advised to start sessions when the first signs of skin laxity or dehydration appear, generally from their thirties.
For patients wishing to treat specific concerns such as acne, hair loss or cellulite, mesotherapy can be considered as soon as these concerns appear.
Patients wishing to prevent skin ageing and maintain good skin hydration can start sessions from the age of 25.
For patients wishing to protect their skin from aggressors such as sun or cold, two sessions are recommended before these periods.
Mesotherapy is particularly suitable during seasonal transitions, when skin is more vulnerable to climatic changes, or before a special event to give skin an instant boost of radiance.
An initial protocol of 4 to 6 sessions spaced two to four weeks apart is often recommended for visible results. Maintenance sessions, generally every 3 to 6 months, then prolong treatment benefits.
What are the different types of
mesotherapy?
Mesotherapy mainly provides hydrating and antioxidant effects. Its benefits depend on the substances injected, injection depth and session frequency.
The benefits of facial mesotherapy, are:
- Radiance boost: restoring luminous, radiant skin is a common expectation. Mesolift is ideal when skin looks dull, tired or dehydrated, restoring vitality, freshness and hydration.
- Skin rejuvenation: this effect is temporary and requires several sessions to maintain it. Skin becomes better hydrated, firmer and more uniform.
- Firming crepey skin: skin hydration improves superficial fine lines.

Hair mesotherapy for baldness and
brittle hair
Hair quality improves, becoming shinier and thicker. This method helps slow hair loss and alopecia and stimulate regrowth.
Mesotherapy for cellulite
Aesthetic mesotherapy is a safe approach to effectively treating cellulite. By directly targeting its causes, treatment helps restore smooth, toned skin. For optimal results, a programme of regular sessions complemented by a healthy, balanced lifestyle is recommended.
Mesotherapy for scars and
acne scars
Mesotherapy has no effect on scars.
The only effective treatments for this concern are peels, ablative laser and hyaluronic acid injections.
Mesotherapy and stretch marks
Mesotherapy is an adjunctive treatment for stretch marks: mesotherapy sessions do not remove stretch marks. The only improvement achievable in stretch marks is through fractional ablative laser.
Mesotherapy aims to:
- Stimulate collagen and elastin production, two proteins essential for skin regeneration. This improves the appearance of white and red stretch marks.
- Improve skin quality and firmness.
- Reduce the inflammation responsible for the red colour of stretch marks.
Dr Romano prepares a personalised mixture of injected ingredients according to the patient's needs.
Anti-ageing mesotherapy
Anti-ageing mesotherapy deeply revitalises the skin, improves elasticity and reduces wrinkles by stimulating collagen and elastin production.
This treatment therefore targets signs of ageing for firmer, more radiant, rejuvenated skin.
Skin mesotherapy
Skin mesotherapy is an effective solution for improving skin quality.
This technique intensely hydrates the skin, evens the complexion and improves radiance. It is ideal for revitalising tired, dull or dehydrated skin.
Mesotherapy for acne
Mesotherapy for acne directly targets the causes of this skin condition.
Benefits include:
- Regulation of sebum production.
- Stimulation of cellular regeneration.
- Reduction of inflammatory acne lesions.
- Preventive action: this method reduces the appearance of new lesions.
Mesotherapy must not be performed during the inflammatory phase, as this would worsen the inflammatory flare and introduce germs deeper into the skin, causing infections.
The mesotherapy mixture contains vitamin A to regulate sebum production and reduce inflammation; ginkgo biloba to reduce sebum production; B vitamins to reduce inflammatory hyperpigmentation; and a mixture of vitamins, hyaluronic acid and antioxidants to hydrate the skin.
Body mesotherapy
Mesotherapy ingredients are injected throughout the body to revitalise, firm and hydrate skin.
Body skin changes over time. Applying creams is insufficient to nourish it. Skin becomes dry, dull and crepey.
Sessions can be preventive, combating skin dryness and loss of firmness. In this case, one session every four to six months is an appropriate maintenance protocol. They may also treat visible signs of ageing or dehydration. Treatment then starts with several closely spaced sessions, with their number and frequency tailored to the patient's skin condition, followed by maintenance at longer intervals.

What happens during a session
mesotherapy session?
Injections are administered to clean, disinfected skin.
Dr Romano uses a mesotherapy gun for the patient's comfort (painless injections using the gun) and to improve treatment quality (the gun allows approximately 200 injections per minute).
Injections are administered at two different depths.
- Intraepidermal: the product is injected one millimetre deep. The intended result is superficial hydration.
- Superficial dermal: 0,1ml of product is injected 2 millimetres deep, forming temporary papules. The aim is to smooth crepey skin.
Make-up and exercise are discouraged immediately after the session but are possible from the following day.
Patients are asked not to apply creams or wash their face for twelve hours afterwards.
Dr Romano always recommends combining treatment with Skinbooster injections or a PRXT33 peel to improve skin texture and ensure lasting deep hydration.
How long does a mesotherapy session last?
A session lasts an average of 10 minutes for the face, neck and décolletage, but can last 30 minutes for the body.
Which areas can be treated with mesotherapy?
Mesotherapy is a versatile technique that can treat various body areas according to the patient's needs.
Areas treated to combat signs of ageing and a dull complexion include:
- Face.
- Neck and décolletage.
- Hands.
Areas treated to improve fluid-related cellulite include:
- The abdomen.
- The thighs.
- The buttocks.
- The arms.
The entire body can be treated to improve skin elasticity and hydration and revitalise the skin. For this indication, a 'whole-body' session every six months should be planned.
What are the side effects
of mesotherapy?
Mesotherapy is a safe procedure when performed by an experienced doctor. However, like any medical intervention, it may involve certain side effects.
The most common adverse effects are redness, bruising and tightness at the injection site.
These effects are temporary and disappear within a few hours. Some patients may experience mild tenderness or itching in treated areas.
How many sessions of
mesotherapy are needed?
The number of sessions depends on the condition of the skin or hair and the patient's aesthetic goals. Dr Romano proposes a personalised protocol based on these factors.
During the initial phase, two to three sessions at three-week intervals will suffice for some patients, while others require six sessions at three-week intervals.
During the maintenance phase, one session two to three times a year will be scheduled.
When do results become visible with
mesotherapy?
For facial treatments, improved skin quality and hydration may be noticed from the first sessions, with more pronounced results after several treatments.
For hair treatments, reduced hair loss and improved density may be observed after 3 to 4 sessions, with optimal results after a few months.
For cellulite treatments, initial improvement is visible after 2 to 3 sessions, but significant results generally appear after 8 to 10 sessions.
How long do results last
of mesotherapy?

Duration varies according to individual response and the specific treatment. Effects generally last several months. Regular maintenance sessions should be planned to preserve treatment benefits.
Mesotherapy vs Skinboosters: what is the difference for your skin?
Many patients have heard of injectable treatments for improving skin quality. Mesotherapy and Skinboosters are among the best known. Although they may seem similar, they have different goals and are performed differently. The choice depends on the skin's needs, condition and the desired result. Advice from an experienced doctor is therefore essential to choose the most suitable technique.
Mesotherapy involves injecting very small amounts of vitamins, minerals, amino acids, peptides or low-concentration hyaluronic acid into superficial skin layers. It is particularly useful for dehydration, fine lines, loss of elasticity and even certain hair concerns. A Skinbooster is a hyaluronic acid specifically formulated to hydrate skin deeply and improve its quality. Skinboosters are mainly indicated for restoring radiance, smoothing fine lines and improving skin density.
These treatments also differ in injection depth and technique. Mesotherapy injections are very superficial. Skinboosters are injected deeper, into the middle or deep dermis, using more precise techniques such as boluses, fanning or retrograde threading.
Mesotherapy results are visible from the first session and improve gradually after three to five sessions. They last three to six months depending on skin quality and lifestyle. Skinboosters provide longer-lasting hydration and skin quality improvement. Effects are often visible from the first session, but a second may be offered four to six weeks later to optimise results. Effects may last six to twelve months, sometimes longer, depending on the product and the patient's skin.
How much does a mesotherapy session cost in Geneva?
A mesotherapy session in Geneva costs 300 CHF.
The price of a session of mesotherapy in Geneva depends on several factors.
- Treatment type: mesotherapy has multiple indications, including skin rejuvenation, cellulite reduction and hair loss. Each treatment has a different cost depending on complexity, the size of the treatment area and products used.
- Number of sessions required.
- Products used: the quality, quantity and type of products injected.
- Doctor's experience: recognised expertise in aesthetic mesotherapy.
The recommended number of sessions may vary according to the indication (radiance, hydration, hair loss, skin laxity, etc.) and each patient's response. A personalised protocol is therefore always proposed during the first medical consultation.
A multicentre randomised trial assessed the effectiveness of three hyaluronic acid mesotherapy sessions combined with a moisturising cream compared with the cream alone. The results showed a greater reduction in fine lines around the eyes, on the neck and on the décolletage at days 75 and 120, as well as improved facial radiance. Increased skin hydration was also observed after the final session. These findings apply to the formulation and protocol studied in a trial funded by the product manufacturer.
Source: Fanian et al., Journal of Dermatological Treatment, 2023.
A clinical study involving 50 participants assessed two hyaluronic acid mesotherapy formulations using a protocol of four sessions fifteen days apart. The results showed improvements in skin radiance, texture and firmness. Skin biopsies also revealed an increase in type I collagen. These findings apply to the formulations studied and should be interpreted cautiously because there was no placebo group.
A controlled study compared hyaluronic acid microinjections on the back of one hand with saline on the other. Among the 18 participants who completed the study, 13 showed ultrasound improvement in the dermal area studied after four weeks. In these responders, improvement persisted during the monthly maintenance protocol. These data involve a small sample and an ultrasound outcome, with repeated injections.
Frequently asked questions about mesotherapy
Is mesotherapy painful?
Mesotherapy is generally well tolerated by most patients, but sensations depend on individual sensitivity and the area treated. Some patients may feel a slight prick or tingling.
Very fine needles are used. An anaesthetic cream may be applied beforehand for particularly sensitive patients, but this is discouraged because it reduces skin absorption of injected products.
Is mesotherapy safe?
Yes, mesotherapy is a risk-free procedure when performed by a trained, experienced doctor. Products are biocompatible and specifically formulated for this type of injection. As with any treatment, however, it is important to discuss your medical history and expectations with your doctor beforehand.
What precautions should be taken after a mesotherapy session?
After mesotherapy, avoid sun exposure, intense physical activity and hot baths for at least 24 to 48 hours. A moisturiser is also recommended, and washing the face on the day of treatment should be avoided.
Who is a good candidate for mesotherapy?
Mesotherapy is ideal for those wishing to improve skin appearance or treat hair loss non-invasively. A medical consultation is necessary to determine suitability.
Can mesotherapy be used for hair?
Yes, mesotherapy can treat hair loss and improve hair density. Scalp injections stimulate hair follicles, promoting regrowth and strengthening existing hair.
Who is allowed to perform mesotherapy?
Mesotherapy is a regulated medical procedure. Only doctors may perform it.
Aesthetic mesotherapy: who should you consult?
Consulting an experienced doctor is recommended for aesthetic mesotherapy.
What is the U225 gun?
The U225 gun is an advanced medical device used in mesotherapy for precise, controlled injections. Originally designed for delicate medical applications, it has been adapted to aesthetic medicine to provide greater comfort and optimise results. The U225 gun’s advanced technology regulates injection depth, speed and volume, reducing pain: the procedure is completely painless.
What product is injected in aesthetic mesotherapy?
Products used in aesthetic mesotherapy are carefully selected according to the patient's specific needs and treatment goals. The mixture generally contains vitamins (such as A, C and E), minerals, amino acids, antioxidants, hyaluronic acid and other ingredients selected to suit skin needs and the indication.
Is mesotherapy effective?
Mesotherapy is recognised for its effectiveness in aesthetic medicine, particularly for treating various skin and hair concerns.
This method stimulates collagen and elastin production, improves microcirculation and deeply hydrates skin, resulting in firmer, more radiant and visibly rejuvenated skin.
For people with hair loss, wrinkles, skin laxity or stretch marks, this procedure provides convincing results with gradual, lasting improvement in skin or scalp quality.
However, effectiveness depends on several factors, including regular sessions, product quality and individual characteristics. Several sessions are needed for optimal results, with maintenance treatments to preserve effects.
What is the difference between mesotherapy and microneedling?
Mesotherapy and microneedling are two popular aesthetic medicine techniques, but differ in technique, results and goals.
Mesotherapy is an injection technique delivering essential nutrients directly into the skin. It aims to nourish, hydrate and revitalise skin from within, stimulating collagen production and improving skin quality and elasticity.
Microneedling uses a roller or device fitted with microneedles that create tiny punctures on the skin's surface. These trigger natural healing, stimulating collagen and elastin production. Although serums or products are often applied during or after microneedling, the technique itself does not involve injecting substances. It is particularly effective for improving skin radiance and enlarged pores.
The techniques can complement each other. The choice depends on the patient's specific needs and desired results.
Are mesotherapy and mesolift the same thing?
Mesotherapy is used on both the face and body for aesthetic or medical concerns (muscle pain, for example).
Mesolift is specifically facial mesotherapy. Its main aim is skin rejuvenation through essential nutrients, vitamins and minerals, helping improve elasticity, firmness and complexion.
Can mesolift be combined with other aesthetic medicine treatments?
Yes, mesolift can be combined with other aesthetic medicine treatments for more comprehensive, synergistic results. A peel may be performed beforehand to remove dead skin cells and prepare for better absorption of injected products. Afterwards, radiofrequency or LED light therapy sessions may be considered to stimulate collagen production and improve radiance.