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BOTULINUM TOXIN : 5 QUESTIONS BEFORE INJECTIONS

Dernière mise à jour : 26 June 2026

Questions about botulinum toxin no longer concern only forehead or frown lines. Today, patients mainly ask when to start, the risk of changing expressions, the value of preventive treatment and the consequences of repeated injections. These five questions help explain what botulinum toxin can genuinely offer, as well as its limitations.

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1. Do you really need to wait for wrinkles before starting botulinum toxin?

No. There is no need to wait until wrinkles are established and visible at rest before considering botulinum toxin injections. Treatment may be offered when muscle contractions start repeatedly marking the skin.
Expression lines first appear during facial movements: frowning, raising the forehead or smiling. Initially, they disappear completely at rest. With time and repeated contractions, they may gradually remain visible even when muscles are no longer contracting.
Botulinum toxin may have preventive value before this permanent establishment. By reducing activity in the muscles responsible for expression lines, it limits repeated contractions gradually contributing to their formation.
This does not mean injections should routinely begin at 25, 30 or 35. Two people of the same age can have very different indications according to muscle activity and how their skin becomes marked.
The right time to start botulinum toxin therefore depends on the first expression lines and their progression, not a specific age.

2. Can you have botulinum toxin injections without others noticing?

Yes. Subtle treatment is possible when reduced muscle activity remains compatible with natural facial dynamics.
The idea that a successful injection should eliminate every contraction is now widely questioned. Many patients instead wish to retain expressions: raising eyebrows, smiling naturally or even continuing to frown slightly.
Dose is only part of the equation. Injection location and the balance between facial muscles are equally important.
On the forehead, for example, the frontalis muscle raises the eyebrows. Weakening it excessively can change the eye area even if horizontal lines are perfectly erased. Conversely, deliberately retaining some activity preserves more movement.
The result can therefore be visible to the patient without others identifying an injection: the face looks less wrinkled but continues functioning harmoniously.
Treatment must therefore be planned around a specific objective, because softening a wrinkle and immobilising a muscle are different aims.

3. “Baby botulinum toxin”, microdoses: are they really better?

No. “Baby botulinum toxin” or microdoses are not automatically better than conventional treatment. Results mainly depend on adapting dose and technique to each patient.
Low doses may be appropriate when the aim is to reduce certain contractions while retaining substantial facial movement. But a lower dose alone does not guarantee a more natural result.
A strong muscle may be undertreated if too little is injected. Conversely, a weaker muscle may need very moderate correction. Dose must therefore be adapted to anatomy, sex, muscle mass, treated area and desired result.
A distinction should also be made between “baby botulinum toxin”, generally meaning reduced doses, and certain “microtoxin” techniques based on very superficial injections. However, these terms describe different protocols, sustaining some confusion.
The question is therefore not whether “baby botulinum toxin” is better, but which dose and technique suit the muscle being treated. A personalised dose is preferable to a predetermined number of units or one chosen simply because it matches a trend.

4. What happens if you have botulinum toxin for years and then stop?

Stopping injections does not suddenly age the face or cause more wrinkles because botulinum toxin was discontinued. Muscles gradually recover activity as treatment wears off.
Contractions therefore become visible again and dynamic wrinkles may gradually return.
After several years of regular injections, certain muscles may also have lost some strength or volume through reduced use. Recovery after stopping is not necessarily immediate.
There is sometimes a subjective impression of worsening: for years, the patient has become accustomed to a less marked forehead or softer frown line. When movement returns, the contrast can be substantial. This does not mean botulinum toxin has “damaged” the face.
Ageing has also continued throughout those years. Skin, fat volume and deep structures have changed independently of treatment.
Botulinum toxin therefore does not create aesthetic dependence in the physiological sense. Continuing or stopping remains a choice: stopping gradually restores activity in treated muscles.

5. Is botulinum toxin still the reference anti-wrinkle treatment?

No. Botulinum toxin is effective when a wrinkle is mainly caused by muscle contraction, but does not treat every manifestation of facial ageing.
This distinction has become even more important as available treatments have multiplied.
A frown line appearing when eyebrows contract has a muscular cause. A hollowing cheek is more associated with volume change. Skin with deteriorating texture, diffuse fine lines or photoageing signs needs another approach again.
Hyaluronic acid, Skinboosters, collagen stimulators, lasers, peels and other techniques are therefore not simply interchangeable alternatives to botulinum toxin. They act on different components of ageing.
This evolution also explains why the current approach focuses less on “treating a wrinkle” and more on finding why it appeared.
Assessing the face at rest and in movement distinguishes a mainly muscular wrinkle from a change associated with skin, volume or sagging. Botulinum toxin then retains a precise role: modulating muscle activity when it is genuinely responsible for the observed problem.

Dr Valeria Romano

Article written by Dr Valeria Romano

Dr Valeria Romano supports each patient through a comprehensive approach to facial, body and intimate aesthetics, as well as skin and hair quality. Every treatment is based on a personalised medical assessment.

Learn more about Dr Valeria Romano
Contact Dr Valeria Romano : +41 78 209 02 89 dr.romano.valeria@gmail.com

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