ARE AESTHETIC INJECTIONS PAINFUL ?

Anti-aging injections, anti-wrinkle Geneva

Among the most common questions expressed during an initial consultation, the issue of pain systematically arises : are the injections painful ? This concern is legitimate, especially since it involves a procedure that breaks the skin in sensitive areas of the face or neck.
However, technical advances, the use of suitable local anesthesia, and the quality of current products now make it possible to perform injections under practically painless conditions, provided they are carried out in a strict medical setting.
It is nevertheless important to distinguish between the different types of possible pain, to understand what causes them, and to explain the means of avoiding or effectively alleviating them.

Contents

What are the possible causes of pain during an aesthetic injection ?

The potential pain experienced during an injection depends on several combined factors, which must be assessed and controlled by the doctor :

  • The nature of the injected product : some products are more viscous or require greater injection pressure, which can cause temporary discomfort. This is particularly the case with highly cross-linked hyaluronic acids or tissue stimulators injected in depth.
  • The anatomical area concerned : some regions are more sensitive than others. The lips, the peri-orbital region, or the nose are areas where nerve density is high, and are therefore more likely to generate a painful sensation if anesthesia is not adequate.
  • The technique used : an injection that is too rapid, poorly controlled depth, or excessive manipulation of the skin can increase discomfort.
  • The equipment used : ultra-fine needles or blunt-tip cannulas considerably reduce local microtraumas.

What is the pain according to the type of injected product ?

Not all products used for aesthetic injections cause the same level of discomfort or painful sensation during injection. The viscosity, the temperature of the gel, the required volume, or the presence or absence of integrated lidocaine influence the patient’s perception.

  • Cross-linked hyaluronic acid : the denser the product, the greater the injection pressure required, which can cause a stretching sensation. This type of product is used in depth (cheekbones, chin, jawline) where sensitivity is lower.
  • Skinboosters or very fluid gels : these products are injected in a superficial layering, sometimes in multiple micro-injections. The sensation is comparable to small pricks, well tolerated.
  • Botulinum toxin : injected in very small volumes, with extremely fine needles. The sensation is comparable to a mosquito bite. It is probably the least painful aesthetic injection.
  • Tissue stimulators (Radiesse, Sculptra) : the injected quantity is greater because these products are diluted, and they can create moderate tension during and after the procedure. The addition of lidocaine makes these injections well tolerated.

Which areas are the most sensitive to injection ?

Not all areas of the face react the same way to pain. Some are more sensitive than others. Here is an overview of the most frequently injected areas, presented according to their degree of sensitivity :

  • Very sensitive : lips, nose, eye contour (dark circles), perioral area.
  • Moderately sensitive : nasolabial folds, cheekbones, jawline, temples.
  • Less sensitive : chin, mandibular angle, deep or less mobile areas.

Cannula or needle and patient comfort

The choice between a traditional needle and a blunt-tip cannula directly affects the sensation experienced.

The needle :

  • More precise for superficial areas or where the skin is thin.
  • Can cause a slight prickling sensation at each injection point.
  • Used for the lips, fine lines, or injections in small areas.

The cannula :

  • Less invasive : it glides between the tissues without cutting the capillaries.
  • Less painful, as a single skin entry point is enough to treat a large area.
  • Used for the cheekbones, tear trough, chin, or jawline.

In practice, the cannula is often better tolerated, especially for deep injections or on extensive anatomical areas.

How does pain evolve after multiple sessions ?

A common observation in clinical practice is that pain related to injections noticeably decreases over successive sessions. The first injection is often the most feared ; thereafter, patients approach treatments with greater confidence, as they know what to expect. The memory of pain helps reduce perceived discomfort, and local sensitivity can also diminish over successive sessions.
This progression allows the technique to be adjusted to provide maximum comfort, without the need to modify the aesthetic protocol.

Injections and hormonal cycles : an impact on sensitivity ?

In female patients, it is important to note that sensitivity to pain varies throughout the menstrual cycle. During the premenstrual period, some women experience increased hypersensitivity, making the injection experience slightly more uncomfortable.
When possible, it is advisable to schedule injections outside periods of hormonal tension, especially for sensitive areas such as the lips or tear troughs. This helps optimize overall comfort and avoid an exaggerated perception of sensations.

Are there any contraindications related to pain or sensitivity ?

There is no formal contraindication to aesthetic injections solely related to fear of pain. However, in certain specific cases, increased attention to patient comfort is necessary :

  • People with fibromyalgia, neurological hypersensitivity, or neuropathy.
  • Patients who are very anxious or have needle phobia.
  • People who have had a poorly managed painful experience in the past.

In these patients, pain management involves a relationship of trust, a detailed explanation of the procedure, carefully adapted anesthesia, and a calm and reassuring environment. Under these conditions, the injection is well tolerated in almost all cases.

Pain after aesthetic injections and residual sensations

After an injection, it is possible to feel slight discomfort, local tension, or sensitivity to touch, particularly in highly mobile areas such as the lips or nasolabial fold. These sensations are temporary and usually disappear within 24 to 48 hours, sometimes a little longer.
In some cases, mild swelling or a small bruise can make the treated area temporarily sensitive. This is not true pain, but rather discomfort that can be relieved by applying local cold, using arnica (in cream or granules), and avoiding muscular efforts such as chewing or intense exercise during the first 24 to 48 hours.

What does a patient actually feel ? Is the perceived pain objective ?

The perception of pain is, by definition, subjective : it depends on individual sensitivity, emotional context, stress level, and memory of previous pain. A very anxious patient will perceive sensations more intensely, even if they are minimal.
That is why the quality of the doctor-patient relationship, clear explanation of the treatment steps, and psychological preparation play a fundamental role in injection tolerance. A reassuring approach, a calm environment, and a slow, gentle injection can sometimes transform a feared experience into a comfortable, even painless, procedure.

Can sedation or an anxiolytic be requested to improve comfort ?

In very rare cases, for extremely phobic or hypersensitive patients, a mild anxiolytic (such as hydroxyzine or low-dose alprazolam) may be prescribed before the session. This approach remains exceptional, as most patients, once well informed, tolerate the procedure perfectly.
However, it is important never to minimize expressed anxiety and to offer concrete solutions for patient comfort : prolonged application of anesthetic cream, pauses during the injection, semi-reclined position, relaxing music.

The importance of properly adapted local anesthesia

There are several techniques to minimize the pain experienced by the patient, without compromising the precision of the procedure or the aesthetic outcome.

  • Anesthetic creams : topical lidocaine (EMLA® cream or equivalent) is applied to the skin 30 to 45 minutes before the injection. It anesthetizes the skin surface in most cases, particularly for superficial injections or Skinboosters.
  • Hyaluronic acid containing lidocaine : most next-generation hyaluronic acids already contain an integrated anesthetic (generally 0.3% lidocaine). This significantly reduces pain during the injection.
  • Truncal or infiltrative anesthesia : for certain very sensitive areas, such as the lips, it is possible to perform local anesthesia by injection. This highly effective technique allows completely painless lip injections.
Photo of doctor Valeria Romano in Geneva

Article written by Dr Romano Valeria

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