WHAT IS MESOTHERAPY AND HOW DOES IT HELP HANDS ?

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Hand rejuvenation in Geneva

Mesotherapy is a medical technique developed in the 1950s. It involves the local injection of small doses of active substances (vitamins, hyaluronic acid, minerals, amino acids) into the superficial dermis using very fine needles. Its goal is to act directly on the targeted area while minimizing systemic side effects.
Originally used to treat rheumatic and muscular pain, mesotherapy has gradually found its place in aesthetic medicine. Its effectiveness in treating skin aging, cellulite, hair loss, and circulatory disorders has made it an essential practice in modern aesthetic medicine.

Why do hands age prematurely ?

Hands often reveal the first visible signs of skin aging. Constantly exposed to external aggressions — such as cold, UV rays, household products, or frequent washing — they are particularly vulnerable. Their skin, thinner than that of the face and poor in sebaceous glands, dehydrates easily, which accelerates the loss of suppleness and elasticity.
Over time, the skin of the hands undergoes multiple changes : collagen and elastin production gradually decreases, leading to a loss of firmness and density ; brown spots (lentigines), clear markers of repeated sun exposure, appear ; veins and tendons become more pronounced, a direct consequence of the thinning of subcutaneous tissue.
In response to these changes, cosmetic care alone is generally insufficient to halt the process. It is in this context that mesotherapy proves particularly relevant.

Hand mesotherapy

Mesotherapy performed on the hands aims to restore hydration, improve skin texture, and stimulate the natural production of collagen.
The injected substances are carefully selected according to the skin’s needs. Among the most commonly used active ingredients :

Non-cross-linked hyaluronic acid : a powerful hydrating agent, it attracts water and restores suppleness and radiance to the skin.
Vitamins (A, C, E) : antioxidants, they protect the skin from oxidative stress.
Minerals and trace elements : contribute to cellular balance.
Amino acids : promote the synthesis of structural proteins (collagen, elastin).

The desired effect is twofold : an immediate improvement in skin radiance through hydration, and a progressive rejuvenating effect through cellular stimulation.

Procedure of a hand mesotherapy session

A hand mesotherapy session takes place in a medical office under strict hygiene conditions. After disinfecting the skin, the injections are performed either manually or using an electronic injector, ensuring optimal precision.
Sessions last on average 20 to 30 minutes. They are minimally painful, as the needles used are extremely fine. A topical anesthetic cream can be applied for sensitive patients.
Aftercare is minimal : slight redness, mild swelling, or small bruises may appear, but disappear within 24 to 48 hours.

Who is hand mesotherapy intended for ?

Hand mesotherapy is mainly intended for :

Patients over 35 with early signs of skin laxity or dehydration.
Patients who wish to prevent the effects of aging.
Patients whose hands are particularly exposed to aggressions (sun, cold, frequent washing).
As a complement to other aesthetic treatments (laser, peeling, radiofrequency) to enhance their results.

This technique is contraindicated in cases of allergy to the injected products, active skin infection, pregnancy, or breastfeeding. A prior medical assessment is always carried out to ensure the indication and safety of the treatment.

What benefits can be expected from hand mesotherapy ?

The results of hand mesotherapy appear progressively. After the first session, one generally observes :

Softer, more radiant skin.
Improved skin quality.
Enhanced hydration.
A subtle but noticeable « défroissé » effect.

From the third session, the results become more noticeable : the skin gains firmness, fine lines are reduced, and the hands appear visibly younger.
The most significant results are generally achieved after four to six sessions spaced fifteen days to three weeks apart, followed by regular maintenance every three to six months to prolong and stabilize the effects.
Mesotherapy does not restore volume (unlike hyaluronic acid injections) and does not treat pigmentation spots (for which a complementary treatment, such as pigment laser, may be considered).

Hand mesotherapy or classic hyaluronic acid injection : what is the difference ?

Unlike filler injections, mesotherapy does not change volume. It acts on the surface to rehydrate and revitalize the skin.
Both approaches can also be combined in a complete hand rejuvenation protocol :

Mesotherapy to improve skin quality.
Cross-linked hyaluronic acid to restore lost volume.
Laser or peeling to reduce pigmentation spots.

This therapeutic synergy allows the hand to be treated as a whole.

The specific benefits of mesotherapy for hand rejuvenation

Mesotherapy is now considered one of the most relevant approaches for treating aging or prematurely altered hands. Its effectiveness is based on a combination of unique characteristics that make it a treatment of choice, both for prevention and correction.

Progressive and natural improvement, without visible transformation : unlike more invasive techniques, mesotherapy respects the anatomy of the hands, preserving their volume and structure. By stimulating the skin’s biological functions in a targeted way, it provides a subtle yet noticeable rejuvenation : the skin becomes more supple, better hydrated, and more radiant. This gentle, progressive, and harmonious transformation appeals to many patients seeking a discreet result.
Dual action, prevention and correction : mesotherapy is suitable both for prevention and therapeutic treatment. When used early, it helps preserve skin quality and delay the first signs of aging (fine lines, dryness, loss of elasticity). On already altered skin, it has a restorative effect : it intensely rehydrates, improves quality, restores firmness, and stimulates collagen production. It is particularly beneficial in cases of wrinkled skin or visible loss of density.
Gentle, non-invasive procedure with no social downtime : performed in a medical office, mesotherapy requires neither general anesthesia, incision, nor recovery time. It fits easily into a busy schedule. Side effects are limited to slight redness, minor temporary bruising, or a tingling sensation. This low impact makes it a favored solution for patients seeking effective yet low-burden treatments.
Personalized and adaptable approach : one of the major advantages of mesotherapy lies in its flexibility. The protocol is adjusted according to the patient’s specific needs : age, skin condition, aesthetic goals. The doctor can customize the composition of the injected mixture, the frequency of sessions, and combine mesotherapy with other treatments (gentle peeling, laser, hyaluronic acid, etc.). This adaptability allows results to be optimized, achieving a natural and harmonious outcome.
Treatment possible in any season : mesotherapy can be performed year-round. It is sufficient to protect the skin from the sun for 48 hours after the session. This feature allows continuity in care, without interruption due to summer periods.

No change in volume : mesotherapy induces no change in volume; it acts exclusively on skin quality, without altering the morphology of the hands. It is thus an ideal solution for patients wishing to improve radiance, evenness of skin tone, and skin suppleness, while maintaining a perfectly natural appearance, with no swelling or visible transformation.
Safe technique for all skin types : mesotherapy is suitable for all skin types, including darker phototypes, which are often at risk of post-inflammatory pigmentation with other treatments. When performed according to best practices, it does not cause pigmentation disorders, making it a safe and suitable option for a diverse patient population — men and women, young and older.

Personalized mesotherapy in Geneva

Each patient being unique, mesotherapy treatment must be personalized according to the quality of their skin, medical history, and aesthetic goals. The doctor pays particular attention to listening, thorough clinical examination, and treatment safety. Hand mesotherapy is fully integrated into protocols for the prevention and correction of skin aging, offering a comprehensive, progressive, and effective approach, while respecting the naturalness of the result.

Article written by Dr Romano Valeria

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Actes de médecine à visée esthétique à Genève