Long neglected in aesthetic medicine protocols, the hands should be treated to achieve overall rejuvenation. They are one of the first parts of the body to show the effects of aging: thinning skin, loss of volume, increased visibility of veins and tendons, pigmented spots. While there are highly effective solutions for the face in aesthetic medicine, it is also possible, through injections, to restore the youthfulness of the hands.
Hyaluronic acid injections are a reference technique in the management of hand skin aging. A frequently asked question is: do these injections need to be performed regularly to maintain their effectiveness? In other words, is it a one-time treatment or a management approach that must be maintained over time?
This page aims to provide a precise, objective answer based on reliable medical data.
Over time, the skin on the back of the hands thins, loses density, and becomes more transparent. This atrophy of the dermis and hypodermis is responsible for a bony, hollowed appearance, often perceived as unattractive. Veins and tendons become more visible, the skin wrinkles, and the overall look reveals the patient’s real age, even after successful facial rejuvenation.
When properly performed and indicated, injections can restore lost volume, deeply hydrate the skin, and stimulate collagen production. The goal is not to artificially mask the effects of time, but to restore the skin’s original quality, thickness, and suppleness.
Two main families of injectable products are used on the hands :
The goal is twofold : an immediate filling effect and a delayed tissue regeneration effect.
Hand rejuvenation through injections – generally with hyaluronic acid – restores volume, reduces the visibility of veins and tendons, and improves skin quality. This treatment provides a natural and immediate result.
However, as with any non-surgical aesthetic procedure, the effects are not permanent. Hyaluronic acid is a resorbable product that gradually degrades over time under the action of the skin’s natural enzymes. Its longevity depends on several factors: the type of product injected, the technique used, the patient’s individual characteristics (metabolism, skin quality), and exposure to external aggressions (UV, smoking, oxidative stress).
Maintenance is recommended every 10 to 12 months to preserve the achieved result. This schedule can be adjusted according to each patient’s specific needs, aesthetic expectations, and skin evolution. It is not always necessary to repeat the entire protocol at each session; in most cases, targeted touch-ups are sufficient, possibly combined with complementary treatments such as Skinboosters or tissue stimulators, to maintain the initial benefits and further improve skin quality.
Maintenance of aesthetic treatments for the hands should be regular, while remaining reasonable and minimally intrusive. It follows a progressive and preventive approach, similar to that used for the face or neck. Contrary to the idea of monthly repetition, follow-up usually consists of one to two sessions per year, depending on the established goals and the products used. A well-designed protocol generally begins with a restructuring phase : an initial session, sometimes followed by a touch-up a month later. Once volume is restored and skin quality improved, maintenance continues at a measured pace to preserve long-term results. These follow-up sessions also allow assessment of skin evolution, adjustment of the type or amount of injected products, and, if necessary, integration of complementary treatments such as mesotherapy, peels, or PRX-T33. This personalized follow-up ensures a harmonious, discreet result in line with each patient’s natural aging. It illustrates an aesthetic approach based on regularity, subtlety, and respect for balance.
A common misconception is that stopping injections would lead to accelerated skin degradation. This is not the case. In reality, the body gradually reabsorbs the injected product.
Without renewal of the injections, the skin gradually returns to its original appearance, without deterioration or rebound effect. However, the advantage of regular treatments is to preserve skin quality : fibroblasts are continuously stimulated, vascularization is improved, and skin quality is maintained.
Injection treatments never “damage” the skin, even if interrupted. But regular care allows for better, slower aging.
The longevity of results obtained after an injection depends not only on the quality of the medical procedure but also on daily care and habits. To prolong the effects of hand rejuvenation treatment, it is essential to create a favorable skin environment that is both protective and nourishing.
Regular application of a rich moisturizer, combined with broad-spectrum sunscreen (SPF 50+), plays a central role in preserving skin elasticity and radiance. Wearing gloves during cold exposure or while performing household or professional tasks also helps maintain the benefits of injections. It is equally important to avoid irritating products, such as harsh soaps or repeated use of alcohol-based gels, which can compromise the skin barrier.
Additionally, a balanced lifestyle has a positive impact: a diet rich in antioxidants, adequate hydration, and moderate sun exposure strengthen skin quality over the long term. Between sessions, certain complementary aesthetic treatments can also be integrated into a comprehensive protocol, notably mesotherapy or PRX-T33 peeling. These gentle techniques stimulate skin regeneration and visibly improve the quality, firmness, and luminosity of the skin on the back of the hands.
By combining appropriate daily habits with targeted treatments, it is entirely possible to optimize and prolong the effects of injections within a coherent and personalized aesthetic strategy.
Every injection on the hands must be preceded by a thorough medical consultation. The clinical examination allows assessment of the skin structure, the degree of tissue atrophy, the presence of spots or vascular lesions, and the quality of the superficial venous network.
Based on this evaluation, a personalized treatment plan can be proposed, clearly defining the number of sessions required, the most suitable products, and the recommended maintenance schedule.
Follow-up over time is equally important. It not only helps maintain a good aesthetic result but also prevents potential side effects or imbalances, rare but possible, when products are injected inappropriately or too closely spaced.
Article written by Dr Romano Valeria
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