WHAT TREATMENTS ARE AVAILABLE FOR HAND WRINKLES ?

Hand rejuvenation in Geneva

Long neglected in favor of the face, the hands are now receiving increasing attention in aesthetic approaches. They are indeed a major social and biological marker : they reveal actual age, lifestyle habits, chronic exposures, and sometimes even underlying pathologies. Among the most visible signs of skin aging, wrinkles on the back of the hands occupy a central place. They are often accompanied by hollowness, loss of firmness, and pigment spots, forming a typical pattern known as « dorsal skin aging ».
Fortunately, today there are several effective and safe treatments to correct hand wrinkles, improve skin quality, restore fullness, and even out the complexion. These treatments can be offered individually or in combination, depending on the degree of aging, skin quality, and the patient’s objectives.

Contents

Understanding the origin of hand wrinkles

Skin aging on the back of the hands relies on multiple and synergistic mechanisms. The progressive loss of subcutaneous fat makes tendinous and venous structures visible ; the alteration of collagen and elastin fibers results in a loss of firmness and suppleness ; slowed microcirculation limits tissue oxygenation and nutrition ; the physiological decrease of hyaluronic acid induces chronic dryness ; finally, photoaging, the predominant factor, promotes the appearance of pigment spots and fine superficial lines.
These degenerative processes are amplified by repeated unprotected sun exposure, smoking, oxidative stress, or insufficient hydration. The skin then loses density and uniformity, wrinkles, hollows, and develops persistent lines, sometimes as early as in the forties, revealing the passage of time prematurely.

Hyaluronic acid injections : restoring volume and smoothing deep wrinkles

The reference treatment for filling pronounced wrinkles and visible hollows on the back of the hands is based on hyaluronic acid injections. This biocompatible and resorbable gel allows the subcutaneous layer to be rebuilt, masking prominent tendons and veins.
The procedure, performed in a medical office under strict asepsis, is minimally painful, carried out using small flexible cannulas, and does not require general anesthesia. The product is injected in a layering technique, into a superficial subcutaneous plane, to restore a harmonious contour. The effect is immediately visible, with a natural appearance and progressive improvement over the following weeks as tissue hydration optimizes.
The duration of results is 10 to 12 months. This treatment can be combined with other techniques for overall hand rejuvenation.

Skinboosters : deeply hydrate and redensify hand skin

If the wrinkles are slight but the skin is thin, wrinkled, or dehydrated, Skinbooster injections represent an ideal alternative or complement. This involves lightly cross-linked hyaluronic acid, injected in a very superficial layering technique, acting as a long-lasting intradermal moisturizer.
The Skinbooster does not add volume, but it provides a visible improvement in skin quality : smoother surface, increased suppleness, and a fresher complexion. It also stimulates fibroblasts, promoting natural collagen and elastin production, thereby delaying the formation of wrinkles.
An initial course of 2 to 3 sessions spaced 3 to 4 weeks apart is recommended, followed by maintenance every 6 to 12 months. The treatment is quick, requires no social downtime, and is particularly appreciated for its discreet yet regenerative effect.

Hand mesotherapy : targeted skin revitalization

Mesotherapy is an intradermal injection technique, involving the delivery of small amounts of revitalizing cocktails directly into the superficial layers of the skin. These solutions generally contain non-cross-linked hyaluronic acid, vitamins (A, C, E, B5), amino acids, trace elements, and sometimes powerful antioxidants.
The goal is to stimulate microcirculation, rehydrate the epidermis, and promote cellular regeneration. The protocol is painless, quick, and requires no social downtime. It is particularly effective in preventing early wrinkles or in maintaining results after volumizing treatments.
Mesotherapy also helps even out skin tone, boost radiance, and slow the appearance of the first signs of aging, especially in young patients exposed to oxidative stress or the sun.

PRX-T33 : biorevitalizing peel without peeling

The PRX-T33 peel is an innovative chemical biorevitalization treatment, combining 33% trichloroacetic acid (TCA), stabilized hydrogen peroxide, and kojic acid. Its uniqueness lies in its deep mode of action without visible exfoliation, making it particularly suitable for delicate areas such as the backs of the hands.
Applied with a massage by a physician, PRX-T33 penetrates the dermis without damaging the epidermis, stimulating collagen production, firming the skin, and reducing fine superficial lines. It also has a lightening effect on minor pigment spots.
This treatment can be performed in a course of 3 to 4 sessions, with applications every 7 to 10 days. It does not cause peeling or intense redness and is suitable for both fair and darker skin types. It is often recommended in combination with injections to improve the overall quality and firmness of the skin on the hands.

Laser photorejuvenation : smoothing fine lines and evening skin tone

Laser photorejuvenation is an effective approach for treating fine lines, pigment irregularities, and stimulating dermal collagen synthesis.
The principle is based on thermal stimulation of fibroblasts through targeted light pulses. The treatment gradually improves the skin’s appearance : fine wrinkles are smoothed, skin texture is refined, spots are reduced, and the complexion becomes more even.
A course of 3 sessions spaced 3 to 4 weeks apart is generally recommended, with progressive results. It is a well-tolerated treatment that can also prepare or maintain the effects of other aesthetic procedures.

Which strategy to choose according to the type of wrinkles ?

The choice of treatment depends on a precise clinical analysis of hand aging. Very lax skin with hollowness requires hyaluronic acid treatment. Wrinkled but still thick skin can benefit from Skinbooster injections, lasers, or PRX-T33 peels. Mesotherapy is often indicated for prevention or maintenance.
In most cases, a combined strategy is the most relevant. It is common, for example, to combine filling hollows with hyaluronic acid, treating spots with laser, and maintaining skin quality with PRX-T33 or Skinboosters. This synergy allows for a global, natural, progressive, and long-lasting rejuvenation of the backs of the hands.

At what age can hand wrinkles be treated ?

It is common to think that aesthetic hand treatments are only for older ages. However, as with the face, signs of skin aging can appear early on the backs of the hands, sometimes as early as the forties, or even earlier in patients chronically exposed to the sun or chemical aggressions (frequent washing, alcohol-based gels, manual professional activities).
The first signs are often subtle : persistent dryness, slight skin folding, loss of radiance, and the appearance of fine lines at rest. At this stage, it is entirely possible — and even recommended — to begin light treatments for preventive and mild corrective purposes, in order to slow the progression of aging and prevent the establishment of deep wrinkles.
Techniques such as mesotherapy, Skinboosters, and PRX-T33 peels can be initiated from 35 to 40 years of age, in patients wishing to maintain optimal skin quality. These treatments aim not to transform, but to strengthen the skin’s defenses, deeply hydrate, and stimulate natural cellular regeneration.
The ideal age to start treatment is not standard, but depends on the actual condition of the skin, heredity, lifestyle, and degree of environmental exposure. A medical consultation allows these factors to be objectively assessed and a personalized, balanced protocol to be developed, perfectly aligned with the patient’s expectations.

Is it possible to prevent hand wrinkles ?

Prevention is a fundamental pillar of any modern aesthetic care. While often applied to the face, this principle equally applies to the hands, whose premature aging is largely avoidable. Several simple steps can help preserve youthful hands and significantly delay visible alterations.
The first preventive measure, often overlooked, is the daily application of sunscreen, even outside the summer months. Natural light — whether passing through windows or filtered through cloudy skies — accelerates photoaging, directly responsible for collagen degradation, wrinkle formation, and pigment spots. Using at least SPF 30 every morning, especially before driving, provides essential baseline protection.
The second essential measure relies on regular and appropriate hydration. Formulas enriched with hyaluronic acid, ceramides, or emollients help preserve the integrity of the hydrolipidic film and prevent chronic dryness, a factor that worsens skin aging. In winter, a rich texture is recommended, whereas in summer, a fluid yet protective formula suffices.
Additionally, dermocosmetic preventive treatments containing antioxidants (vitamins C and E, resveratrol), low-dose retinol, or fruit acids in low concentration can be used occasionally in a nighttime routine. They stimulate cell renewal, smooth the skin surface, and strengthen skin firmness.
Limiting aggravating factors is also essential : avoid harsh washing, wear gloves when using household products, and moisturize systematically after each exposure to water. These simple steps, integrated into an overall lifestyle, constitute a long-term preventive strategy.
Ultimately, hand wrinkles are by no means inevitable. By combining photoprotection, hydration, and targeted care, it is possible to maintain dense, supple, and radiant skin well beyond fifty, without necessarily resorting immediately to medical treatments.

Photo of doctor Valeria Romano in Geneva

Article written by Dr Romano Valeria

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