{"id":19023,"date":"2024-09-12T11:31:06","date_gmt":"2024-09-12T09:31:06","guid":{"rendered":"https:\/\/drromanovaleria.ch\/?p=19023"},"modified":"2026-06-02T21:17:59","modified_gmt":"2026-06-02T19:17:59","slug":"action-botulinum-toxin","status":"publish","type":"post","link":"https:\/\/drromanovaleria.ch\/en\/blog\/action-toxine-botulique\/","title":{"rendered":"How does botulinum toxin work ?"},"content":{"rendered":"<h1>HOW DOES BOTULINUM TOXIN WORK ? <\/h1>\n<p class=\"translation-block\">Botulinum toxin<\/strong> injections are among the most commonly used aesthetic treatments to reduce wrinkles. Although very widespread, the question many people still ask is : how does botulinum toxin actually work ? Indeed, not everyone knows its mechanism of action at the cellular and muscular level, which allows for visible and lasting results.<br>In this article, we will explain in detail how botulinum toxin acts on muscles and neurons, and how this translates into a reduction of wrinkles and muscle contractions.<\/p>\n<p>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/indications-mesotherapie-768x432.webp\" alt=\"image of mesotherapy\" srcset=\"https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/indications-mesotherapie-768x432.webp 768w, https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/indications-mesotherapie-300x169.webp 300w, https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/indications-mesotherapie-1024x576.webp 1024w, https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/indications-mesotherapie-1536x864.webp 1536w, https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/indications-mesotherapie-2048x1152.webp 2048w, https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/indications-mesotherapie-18x10.webp 18w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/><br \/>\n\t\t\t\t\t<a href=\"https:\/\/drromanovaleria.ch\/en\/contact-doctor-romano-valeria\/\"><br \/>\n\t\t\t\t\t\t\t\t\tBook an appointment<br \/>\n\t\t\t\t\t<\/a><\/p>\n<h2>\n\t\t\t\tContents\t\t\t<\/h2>\n<p>\t\t\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M207.029 381.476L12.686 187.132c-9.373-9.373-9.373-24.569 0-33.941l22.667-22.667c9.357-9.357 24.522-9.375 33.901-.04L224 284.505l154.745-154.021c9.379-9.335 24.544-9.317 33.901.04l22.667 22.667c9.373 9.373 9.373 24.569 0 33.941L240.971 381.476c-9.373 9.372-24.569 9.372-33.942 0z\"><\/path><\/svg><br \/>\n\t\t\t\t<svg aria-hidden=\"true\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M240.971 130.524l194.343 194.343c9.373 9.373 9.373 24.569 0 33.941l-22.667 22.667c-9.357 9.357-24.522 9.375-33.901.04L224 227.495 69.255 381.516c-9.379 9.335-24.544 9.317-33.901-.04l-22.667-22.667c-9.373-9.373-9.373-24.569 0-33.941L207.03 130.525c9.372-9.373 24.568-9.373 33.941-.001z\"><\/path><\/svg><br \/>\n\t\t\t\t<svg aria-hidden=\"true\" viewbox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M500 975V858C696 858 858 696 858 500S696 142 500 142 142 304 142 500H25C25 237 238 25 500 25S975 237 975 500 763 975 500 975Z\"><\/path><\/svg>\t\t\t<\/p>\n<h2>What is botulinum toxin ?<\/h2>\n<p class=\"translation-block\">Botulinum toxin is a neurotoxin produced by <em>Clostridium botulinum<\/em> bacteria. Several types exist, but type A is most commonly used medically and aesthetically.<br>Used in medicine for many years, this molecule is recognised for effectiveness and safety when injected by a specialist. It is among Geneva's most valued aesthetic medical treatments.<\/p>\n<h2>The action of botulinum toxin<\/h2>\n<p data-start=\"103\" data-end=\"312\" class=\"translation-block\">Botulinum toxin is one of the most effective known substances for modulating nerve\u2013muscle communication. It temporarily blocks nerve signal transmission.<br>This prevents certain muscles contracting excessively. Targeted relaxation softens expression lines, prevents static wrinkles and gives a rested, naturally rejuvenated face without freezing features when injected precisely and subtly.<br>Its reversible, controlled action makes it a preferred aesthetic medicine treatment in Geneva.<\/p>\n<h2>How does nerve transmission work in muscles?<\/h2>\n<p class=\"translation-block\">To understand the mechanism of action of botulinum toxin, it is essential to understand how muscles normally contract.<br>Muscle movements are controlled by the nervous system. When a signal is sent from the brain or spinal cord to move a muscle, it travels along a motor neuron until it reaches the junction between the neuron and the muscle, called the neuromuscular junction.<br>At this junction, the nerve releases a neurotransmitter called acetylcholine into a small area known as the synaptic cleft (the space between the nerve and the muscle cell).<br>Acetylcholine binds to specific receptors located on the surface of muscle cells, which triggers their contraction.<\/p>\n<h2>Botulinum toxin's mechanism of action on muscles<\/h2>\n<p>Botulinum toxin type A acts directly on this nerve transmission process, blocking the release of acetylcholine and inhibiting muscle contraction.<\/p>\n<p>Inhibition of acetylcholine release: botulinum toxin acts at nerve endings by blocking the release of acetylcholine. It does this by cleaving specific proteins in the vesicles containing acetylcholine, preventing these vesicles from fusing with the nerve cell membrane. In other words, the toxin 'deactivates' the acetylcholine release mechanism.<br \/>Without this neurotransmitter, the muscle cannot receive the signal needed to contract. It therefore remains relaxed.<br \/>Effet temporaire sur les muscles\u00a0: l&rsquo;effet de la toxine botulique est temporaire, car les cellules nerveuses finissent par g\u00e9n\u00e9rer de nouvelles terminaisons capables de lib\u00e9rer de l&rsquo;ac\u00e9tylcholine. Cela signifie que les r\u00e9sultats de l\u2019injection durent g\u00e9n\u00e9ralement entre 3 et 6 mois, selon la zone trait\u00e9e et le m\u00e9tabolisme du patient.<br \/>Precise muscle targeting: the doctor targets specific muscles to relax only areas responsible for expression lines. For forehead lines or crow's feet, injections target muscles causing repeated contractions there. This smooths treated skin while preserving natural expression.<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<h2>Effect on expression lines<\/h2>\n<p data-start=\"281\" data-end=\"666\" class=\"translation-block\">Botulinum toxin selectively reduces muscles responsible for expression lines. Repeated movements gradually produce forehead lines, frown lines between the eyebrows and crow's feet around the eyes. Constant contractions eventually mark skin even at rest.<br>Temporarily relaxing these muscles gradually softens expression lines. Skin becomes smoother, eyes more rested and features softer without losing naturalness. Precise injections preserve harmony for subtle, elegant results perfectly suited to Geneva's aesthetic expectations.<\/p>\n<h2>Muscle relaxation process<\/h2>\n<p data-start=\"58\" data-end=\"463\" class=\"translation-block\">Muscle relaxation is not immediate. After injection, the product acts on the targeted muscle and soon begins blocking nerve signals. Although some notice improvement after two to three days, optimal results generally appear on the seventh day.<br>Effects then last an average of three to six months while nerve endings gradually regenerate. As muscle activity returns, expression lines may reappear, explaining the need for maintenance.<\/p>\n<h2>Differences between botulinum toxin and other aesthetic treatments<\/h2>\n<p class=\"translation-block\">Distinguish botulinum toxin from injectables such as hyaluronic acid, as their actions and indications differ.<br>Botulinum toxin mainly relaxes muscles responsible for expression lines, also called dynamic wrinkles. Limiting repeated contractions at the forehead, frown lines and crow's feet prevents new wrinkles and softens existing ones.<br>Hyaluronic acid is a dermal filler correcting static wrinkles, restoring lost volumes, redefining contours, enabling facelift techniques and deeply hydrating skin (Skinboosters). Its action is structural and volumising, while botulinum toxin acts on muscle dynamics.<br>These approaches often complement each other: botulinum toxin smooths and prevents, while hyaluronic acid fills and restores harmony. Combined in a personalised protocol, they produce balanced, natural, lasting results.<\/p>\n<h2>Long-term effects of botulinum toxin<\/h2>\n<p>Repeated botulinum toxin injections have long-term benefits. When muscles remain relaxed, wrinkles form less easily, potentially slowing ageing in treated areas. However, reasonable intervals (4 to 6 months) are essential to avoid developing tolerance.<\/p>\n<h2>Safety of botulinum toxin injections<\/h2>\n<p>Botulinum toxin injections are considered safe when performed by an experienced doctor. Common side effects are minor, such as injection-site redness or bruising, generally disappearing within days.<\/p>\n<p>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"763\" height=\"908\" src=\"https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/photo-docteur-romano-valeria.webp\" alt=\"Photo of doctor Valeria Romano in Geneva\" srcset=\"https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/photo-docteur-romano-valeria.webp 763w, https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/photo-docteur-romano-valeria-252x300.webp 252w, https:\/\/drromanovaleria.ch\/wp-content\/uploads\/2024\/07\/photo-docteur-romano-valeria-10x12.webp 10w\" sizes=\"auto, (max-width: 763px) 100vw, 763px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/p>\n<p>Article written by <a href=\"https:\/\/drromanovaleria.ch\/en\/\">Dr Romano Valeria<\/a><\/p>\n<p>SHARE THIS ARTICLE ON<\/p>\n<p>\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" viewbox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z\"><\/path><\/svg><br \/>\n\t\t\t\t\t\t\t\t\t\tLinkedIn\t\t\t\t\t\t\t\t\t<\/p>\n<ul>\n<li>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:dr.romano.valeria@gmail.com\"><br \/>\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" viewbox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg><br \/>\n\t\t\t\t\t\t\t\t\t\tdr.romano.valeria@gmail.com<br \/>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n<li>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"tel:+41%2078%20209%2002%2089\"><br \/>\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" viewbox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M497.39 361.8l-112-48a24 24 0 0 0-28 6.9l-49.6 60.6A370.66 370.66 0 0 1 130.6 204.11l60.6-49.6a23.94 23.94 0 0 0 6.9-28l-48-112A24.16 24.16 0 0 0 122.6.61l-104 24A24 24 0 0 0 0 48c0 256.5 207.9 464 464 464a24 24 0 0 0 23.4-18.6l24-104a24.29 24.29 0 0 0-14.01-27.6z\"><\/path><\/svg><br \/>\n\t\t\t\t\t\t\t\t\t\t+41 78 209 02 89<br \/>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Les injections de toxine botulique sont l&rsquo;un des traitements esth\u00e9tiques les plus utilis\u00e9s pour r\u00e9duire les rides. Bien que tr\u00e8s r\u00e9pandues, la question que beaucoup de personnes se posent reste : comment la toxine botulique agit-elle r\u00e9ellement ? <\/p>","protected":false},"author":2,"featured_media":13030,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-19023","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Comment les toxines botuliques agissent ? - Gen\u00e8ve - Dr Romano<\/title>\n<meta name=\"description\" content=\"D\u00e9couvrez le mode d&#039;action des toxines botuliques et comment elles bloquent les signaux nerveux pour d\u00e9tendre les muscles. Cet article explique en d\u00e9tail leur fonctionnement et leurs effets, tant pour des usages esth\u00e9tiques que th\u00e9rapeutiques\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/drromanovaleria.ch\/en\/blog\/action-botulinum-toxin\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Comment les toxines botuliques agissent ? - Gen\u00e8ve - Dr Romano\" \/>\n<meta property=\"og:description\" content=\"D\u00e9couvrez le mode d&#039;action des toxines botuliques et comment elles bloquent les signaux nerveux pour d\u00e9tendre les muscles. 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