{"id":64198,"date":"2026-04-22T19:21:22","date_gmt":"2026-04-22T17:21:22","guid":{"rendered":"https:\/\/drromanovaleria.ch\/?page_id=64198"},"modified":"2026-06-05T12:52:47","modified_gmt":"2026-06-05T10:52:47","slug":"assaults","status":"publish","type":"page","link":"https:\/\/drromanovaleria.ch\/en\/agressions\/","title":{"rendered":"Skin stressors"},"content":{"rendered":"

SKIN CARE AND DAILY ASSAULTS<\/h1>\n

\n\t\t\t\tContents\t\t\t<\/h2>\n

\t\t\t\t\t\t\t\t\t\t<\/path><\/svg>
\n\t\t\t\t<\/path><\/svg>
\n\t\t\t\t<\/path><\/svg>\t\t\t<\/p>\n

The skin is a living, dynamic organ that constantly interacts with its environment. Although skin ageing is partly determined by genetics, it is now clearly established that most visible skin changes are linked to external and internal factors. This is the context in which the exposome has emerged as a fundamental concept in dermatology and aesthetic medicine.
Understanding the skin exposome makes it possible to adopt a comprehensive, consistent and effective approach to preventing and managing skin ageing. In Geneva, where urban lifestyles expose the skin to multiple stressors, this approach is particularly relevant.<\/p>\n

\n\t\t\t\t\t\t\t\tSun\t\t\t\t\t\t\t<\/h3>\n

\t\t\t
\n\t\t<\/a><\/p>\n

\n\t\t\t\t\t\t\t\tSmoking\t\t\t\t\t\t\t<\/h3>\n

\t\t\t
\n\t\t<\/a><\/p>\n

\n\t\t\t\t\t\t\t\tPollution\t\t\t\t\t\t\t<\/h3>\n

\t\t\t
\n\t\t<\/a><\/p>\n

\n\t\t\t\t\t\t\t\tCold\t\t\t\t\t\t\t<\/h3>\n

\t\t\t
\n\t\t<\/a><\/p>\n

\n\t\t\t\t\t\t\t\tStress\t\t\t\t\t\t\t<\/h3>\n

\t\t\t
\n\t\t<\/a><\/p>\n

What is the exposome ?<\/h2>\n

The term exposome refers to all the exposures an individual experiences throughout life, whether environmental, behavioural or emotional. Introduced into science to complement the concept of the genome, it helps explain how the environment affects health.
Applied to the skin, the exposome encompasses all external and internal factors influencing its condition, ageing and capacity to regenerate. Unlike intrinsic ageing, which depends on age and genetics, exposome-related ageing is largely modifiable.
This concept is essential in aesthetic medicine. It moves beyond a purely corrective approach to incorporate comprehensive prevention based on understanding the causes.<\/p>\n

The skin exposome<\/h2>\n

The skin exposome involves constant interaction between external stressors and internal factors specific to each individual. These two dimensions act cumulatively and often synergistically.
External factors include ultraviolet radiation, air pollution, climatic variations and artificial light. Internal factors include stress, sleep, diet and hormonal changes.
This interaction explains why two people of the same age can have very different skin quality.<\/p>\n

External environmental stressors<\/h2>\n

External environmental stressors have a direct impact on the skin<\/p>\n

Ultraviolet radiation : the leading cause of skin ageing\u00a0<\/h3>\n

UV radiation is the leading cause of premature skin ageing. It is responsible for what is known as photoageing.
UV radiation causes significant oxidative stress, generating free radicals that break down collagen and elastin. It also contributes to pigmentation and loss of skin elasticity.
Chronic sun exposure, even at moderate levels, has a cumulative effect on the skin.<\/p>\n

Pollution<\/h3>\n

Air pollution is now recognised as a key factor in skin ageing. Fine particles and pollutant gases penetrate or settle on the skin, causing oxidative stress and chronic inflammation.
It impairs the skin barrier, promotes dehydration and contributes to a dull complexion, pigmentation<\/a> and wrinkles<\/a>.<\/p>\n

Blue light<\/h3>\n

Blue light, emitted by screens and certain light sources, is one of today's skin stressors. It penetrates deep into the skin and contributes to free radical formation.
Its role in skin ageing is still being studied, but current evidence suggests an impact on pigmentation and oxidative stress.<\/p>\n

Climatic conditions<\/h3>\n

Climatic conditions directly affect skin quality. Cold and wind impair the skin barrier, leading to dryness and sensitivity.
Sudden temperature changes, common in winter, weaken the skin and disrupt its ability to adapt.<\/p>\n

The internal exposome \u00a0<\/h2>\n

Emotional and physiological factors play an important role in skin ageing and in aesthetic and functional changes to the skin.<\/p>\n

Stress : an accelerator of skin ageing<\/h3>\n

Chronic stress directly affects the skin through cortisol production. It reduces collagen synthesis, impairs barrier function and promotes inflammation.
It also causes visible signs such as a dull complexion, dark circles<\/a>, acne and skin sensitivity.<\/p>\n

Sleep : a pillar of skin regeneration<\/h3>\n

The skin regenerates mainly at night. Insufficient or poor-quality sleep impairs repair mechanisms and accelerates skin ageing.
Lack of sleep produces a tired complexion, diminished radiance and more pronounced signs of ageing.<\/p>\n

Diet<\/h3>\n

An unbalanced diet low in antioxidants promotes oxidative stress and inflammation.
Conversely, a diet rich in vitamins, minerals and essential fatty acids helps maintain healthy, resilient skin.<\/p>\n

Biological mechanisms of the skin exposome<\/h2>\n

Exposome-related stressors act mainly through three mechanisms : oxidative stress, with free radical production ; chronic low-grade inflammation ; impairment of the skin barrier.
These mechanisms lead to gradual deterioration of dermal structures, reduced regenerative capacity and a decline in overall skin quality.<\/p>\n

Effects of the exposome on the skin : clinical signs<\/h2>\n

The effects of the exposome appear as visible, often progressive signs :<\/p>\n